Overview
- Editors:
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Yury Verlinsky
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Reproductive Genetics Institute, Chicago, USA
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Anver Kuliev
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Reproductive Genetics Institute, Chicago, USA
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Table of contents (34 chapters)
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Embryological Aspects of Preimplantation Genetics
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Micromanipulation and Biopsy of Gametes and Preembryos
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- Jacques Cohen, Mina Alikani, Henry Malter, Beth Talansky, Michael Tucker, Sharon Wiker et al.
Pages 63-74
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Genetic Analysis of Gametes and Preembryos
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- Norman Arnheim, Honghua Li, Xiangfeng Cui, William Navidi
Pages 121-130
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- Charles M. Strom, Gloria Enriquez, Svetlana Rechitsky
Pages 131-138
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- Eleni H. Kontogianni, Kate Hardy, Alan H. Handyside
Pages 139-145
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- Jamie A. Grifo, David C. Ward, Ann Boyle
Pages 147-152
About this book
Yury Verlinskyand Anver Kuliev Reproductive Genetics Institute, Illinois Masonic Medical Center, 836 W. Wellington chicago, IL 60657 Although introduction of a first trimester prenatal diagnosis by chorionic viIIus sampling (CVS) has considerably improved the possibility for prevention of genetic diseases, it requires a selective abortion in case of an affected fetus. Following the direction of an earlier prenatal diagnosis and to avoid the need for abortion, preimplantation genetic diagnosis has been initiated based on polar body removal and pre-embryo biopsy. The First International symposium on Preimplantation Genetics, Chicago, September 17-19, 1990, was organized to explore these important developments, to review the state of knowledge in the field, and to address existing problems to be solved for developing and improving current approaches for preimplantation diagnosis of genetic disorders. A growing interest in the subject was obvious from the wide attendance of the meeting: over 250 scientists from 19 countries participated. This was the first attempt to put together the advances in different areas of basic and applied research relevant to Preimplantation Genetic Diagnosis, with the multidisciplinary scientific program including the sessions on embryology, micromanipulation and biopsy, genetic analysis of gametes and pre-embryos, IVF, gene expression and gene therapy, and ethical and legal issues. The deliberations of the Symposium presented in the above mentioned sessions, which comprise the contents of correspond ing sections of the Proceedings, open a newarea in medical research based on the interaction of IVF and New Genetics.
