Advances in Experimental Medicine and Biology

Infections in the Immunocompromised Host

Laboratory Diagnosis and Treatment

Authors: Actor, P., Evangelista, A., Poupard, J., Hinks, E.

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About this book

The subject matter of this volume, the basis for which was a conference held in Philadelphia which focused on the subject of infections, including their diagnosis and treatment, in immunocompromised individuals. The material is of particular importance today when placed against the background of the rapid spread of acquired immunodeficiency syndrome (AIDS). The first section dealt with the general subject of the immunocompromised host. Here, reviewed in detail, were the epidemiological and clinical aspects of opportunistic infections in patients with defective immune responses. It is widely acknowledged that infections are a major complication of the neoplastic process. Cancer-bearing patients are more prone to certain kinds of infectious and cancer chemotherapy almost always increases susceptibility to such infections. Depending upon the basic disease process of the cancer, a specific array of infectious diseases can be predicted. Patients altered in thymus-derived lymphocyte populations or mononuclear phagocyte capabilities resulting in defects in cell mediated immunity or delayed hypersensitivity become highly susceptible to certain groups of organisms, whereas, profoundly neutropenic patients usually become infected with different organisms. The types of infections noted are relatively predictable for the type of immune defect, with some variations according to epidemiological factors. Major advances have been made in the early diagnosis and treatment of infectious complications with increasingly effective antimicrobial agents and increasing knowledge of their use. The application of so-called preventive procedures has had limited value to date, including immunotherapy, which appears to hold much promise.

Table of contents (13 chapters)

Table of contents (13 chapters)

Buy this book

eBook $109.00
price for USA in USD
  • ISBN 978-1-4684-1259-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Softcover $139.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Infections in the Immunocompromised Host
Book Subtitle
Laboratory Diagnosis and Treatment
Authors
Series Title
Advances in Experimental Medicine and Biology
Series Volume
202
Copyright
1986
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4684-1259-8
DOI
10.1007/978-1-4684-1259-8
Softcover ISBN
978-1-4684-1261-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XII, 208
Number of Illustrations
2 b/w illustrations
Topics