Oxygen Free Radicals in Tissue Damage

Authors: TARR,M., SAMSON,F.

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About this book

Oxygen free radicals and other reactive oxygen species are being postulated as causal agents in an increasing number of pathological conditions. Indeed, some investigators are suggesting that highly destructive reactive oxygen species are the final common path lead­ ing to tissue damage following a wide variety of insults including trauma, hypoxia, ischemia, hyperoxia, radiation, some toxins, and even strenuous athletic pursuits. But, as Robert Floyd points out, "Proof of the importance of oxygen free radicals and the oxidative damage they initiate depend on unequivocal evidence for the pres­ ence of free radicals and a clear association of their formation with the induction of the dysfunction of pathological conditions. " Since such proof does not come easily, there have been and will continue to be many controversies regarding the role played by reactive oxygen species in tissue damage. There have been many recent reviews of the chemistry and pos­ sible role of reactive oxygen species in many types of organ dys­ functions, tissue damage, degenerative diseases, and aging. This book is not such a review. Rather it presents for a diverse audience of physical-organic chemists, biochemists, medical researchers, and other investigators of pathophysiology, discussions of a variety of is­ sues important for understanding reactive oxygen species and their role in tissue damage.

Table of contents (14 chapters)

Table of contents (14 chapters)
  • Getting Along With Oxygen

    Pages 1-11

    Fridovich, Irwin

  • Oxygen Free Radicals and Tissue Injury

    Pages 12-53

    Borg, Donald C.

  • Photosensitizers as Model Systems to Study Reactive Oxygen Effects in Biological Preparations

    Pages 54-76

    Valenzeno, Dennis P. (et al.)

  • Singlet Oxygen in Biological Systems: A Comparison of Biochemical and Photochemical Mechanisms for Singlet Oxygen Generation

    Pages 77-92

    Kanofsky, Jeffrey R.

  • In Vivo Detection of Oxygen Free Radical Species

    Pages 93-104

    Floyd, Robert A.

Buy this book

eBook $89.00
price for USA in USD
  • ISBN 978-1-4615-9840-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $119.99
price for USA in USD
  • ISBN 978-1-4615-9842-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Oxygen Free Radicals in Tissue Damage
Authors
Copyright
1993
Publisher
Birkhäuser Basel
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-9840-4
DOI
10.1007/978-1-4615-9840-4
Softcover ISBN
978-1-4615-9842-8
Edition Number
1
Number of Pages
X, 297
Topics