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Dietary Phenylalanine and Brain Function

  • Book
  • © 1988

Overview

Editors:
  1. Richard J. Wurtman

    1. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Eva Ritter-Walker

    1. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, USA

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (48 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Factors Affecting Blood Phenylalanine Levels

    1. Front Matter

      Pages 1-1
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    2. Control of Plasma Phenylalanine Levels

      • Benjamin Caballero, Richard J. Wurtman
      Pages 3-12

    3. Adrenergic Influence on Plasma and Brain Concentrations of Phenylalanine and Other Large Neutral Amino Acids in Rats

      • Tomas Eriksson, Arvid Carlsson
      Pages 13-17

    4. Effect of Aspartame on Plasma Phenylalanine Concentration in Humans

      • L. J. Filer Jr., Lewis D. Stegink
      Pages 18-40

    5. Aspartame Consumption in Normal Individuals and Carriers for Phenylketonuria

      • Reuben Matalon, Kimberlee Michals, Debra Sullivan, Louise Wideroff, Paul Levy
      Pages 41-52

  3. Blood-Brain Barrier Transport of Phenylalanine

    1. Front Matter

      Pages 53-53
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    2. Phenylalanine Transport at the Human Blood-Brain Barrier

      • William M. Pardridge
      Pages 55-62

    3. Regional Transport of Phenylalanine and Other Neutral Amino Acids Across the Blood-Brain Barrier

      • Richard A. Hawkins, Anke M. Mans, Julien F. Biebuyck
      Pages 63-67

    4. Dual Role of Transport Competition in Amino Acid Deprivation of the Central Nervous System by Hyperphenylalaninemia

      • Halvor N. Christensen, Carlos de Céspedes
      Pages 68-78

  4. Effects of Aspartame on Brain Monoamines and Seizure Thresholds in Experimental Animals

    1. Front Matter

      Pages 79-79
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    2. An In Vivo Study of Dopamine Release in Striatum: The Effects of Phenylalanine

      • Matthew J. During, Ian N. Acworth, Richard J. Wurtman
      Pages 81-86

    3. Effects of Aspartame Ingestion on Large Neutral Amino Acids and Monoamine Neurotransmitters in the Central Nervous System

      • John D. Fernstrom
      Pages 87-94

    4. Aspartame, Phenylalanine, and Seizures in Experimental Animals

      • Judith M. B. Pinto, Timothy J. Maher
      Pages 95-103

    5. Behavioral and Neurological Effects of Aspartame

      • Hugh A. Tilson, Dayao Zhao, N. John Peterson, Kevin Nanry, J.-S. Hong
      Pages 104-110

    6. Role of Monoamines in Seizure Predisposition in the Genetically Epilepsy-Prone Rat

      • Phillip C. Jobe, John W. Dailey
      Pages 111-121

    7. Aspartame Administration Decreases the Entry of α-Methyldopa into the Brain of Rats

      • Timothy J. Maher, Paul J. Kiritsy
      Pages 122-126

    8. The Effect of Aspartame on 50% Convulsion Doses of Lidocaine

      • K. C. Kim, M. D. Tasch, S. H. Kim
      Pages 127-130

    9. Studies on the Susceptibility to Convulsions in Animals Receiving Abuse Doses of Aspartame

      • Silvio Garattini, Silvio Caccia, Maria Romano, Luisa Diomede, Giovanna Guiso, Annamaria Vezzani et al.
      Pages 131-143

    10. General Discussion: Calculation of the Aspartame Dose for Rodents that Produces Neurochemical Effects Comparable to Those Occurring in People

      • Richard J. Wurtman, Timothy J. Maher
      Pages 144-148
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Keywords

Editors and Affiliations

  • Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, USA

    Richard J. Wurtman, Eva Ritter-Walker

Bibliographic Information

  • Book Title: Dietary Phenylalanine and Brain Function

  • Editors: Richard J. Wurtman, Eva Ritter-Walker

  • DOI: https://doi.org/10.1007/978-1-4615-9821-3

  • Publisher: Birkhäuser Boston, MA

  • eBook Packages: Springer Book Archive

  • Copyright Information: Birkhäuser Boston 1988

  • Softcover ISBN: 978-1-4615-9823-7Published: 22 February 2012

  • eBook ISBN: 978-1-4615-9821-3Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIV, 391

  • Topics: Human Physiology

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