Advances in Experimental Medicine and Biology

Molecular Biology and Pathogenesis of Coronaviruses

Editors: Rottier, P. J. (Ed.)

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About this book

The present volume contains the Proceedings of an EMBO Workshop organized in June 1983 by the Institute of Virology, Veterinary Faculty, State University of Utrecht, The Netherlands. Some 70 scientists from 11 countries followed the invitation to present and discuss their recent data on the structure, replication, genetics and pathogenesis of coronaviruses. It was the second international meeting on these viruses; the Workshop, which was held in Zeist near Utrecht followed the example of the Wuerzburg symposium of October 1980. At that time it became clear that coronaviruses are unique in many respects. Once a group of viruses that were defined merely on the basis of their characteristic peplomer morphology, Coronaviridae family members are known today - to be constructed from essentially three polypeptides - to use a "nested set" of 5-6 subgenomic mRNAs in the expression of their large, positive and single stranded RNA genome, - to generate these subgenomic RNAs through specific fusion of non­ contiguous sequences, - to mature by budding from intracellular membranes, - to cause persistent infection with neurological involvement and sometimes immunopathological conditons. These and many other findings have been established only very recently. The articles collected in this book reveal and/or further detail these findings. Since these Proceedings contain the combined scientific presentations of representatives from virtually all laboratories engaged in the field, they provide a fairly comprehensive review of the state of the art in corona­ virology.

Table of contents (45 chapters)

Table of contents (45 chapters)

Buy this book

eBook $84.99
price for USA in USD
  • ISBN 978-1-4615-9373-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Biology and Pathogenesis of Coronaviruses
Editors
  • P. J. Rottier
Series Title
Advances in Experimental Medicine and Biology
Series Volume
174
Copyright
1984
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-9373-7
DOI
10.1007/978-1-4615-9373-7
Softcover ISBN
978-1-4615-9375-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIII, 409
Topics