Vasopressin

1. Front Matter

   Pages i-xviii

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2. Anatomy and Function of the Classic Vasopressin-Secreting Hypothalamus-Neurohypophysial System

   • J. F. Morris, D. B. Chapman, H. W. Sokol

   Pages 1-89

3. Vasopressin Localization and Putative Functions in the Brain

   • R. M. Buijs

   Pages 91-115

4. Development of Vasopressin Systems and Their Functions

   • G. J. Boer

   Pages 117-174

5. Biosynthesis of Vasopressin and Neurophysins

   • William G. North

   Pages 175-209

6. Electrophysiology of the Central Vasopressin System

   • J. B. Wakerley

   Pages 211-256

7. Electrophysiological Actions of Vasopressin in Extrahypothalamic Regions of the Central Nervous System

   • M. Joëls

   Pages 257-274

8. Effect of Neurotransmitters and Neuropeptides on Vasopressin Release

   • Celia D. Sladek, William E. Armstrong

   Pages 275-333

9. Selective Agonists and Antagonists of Vasopressin

   • Maurice Manning, Krzysztof Bankowski, Wilbur H. Sawyer

   Pages 335-368

10. Physiological Effects of Vasopressin on the Kidney

    • Heinz Valtin

    Pages 369-387

11. Cardiovascular Actions of Vasopressin

    • Allen W. Cowley Jr., Jean-François Liard

    Pages 389-433

12. Vasopressin and Endocrine Function

    • George A. Hedge, Linda J. Huffman

    Pages 435-475

13. Vasopressin Receptors in the Brain and Pituitary

    • Fred W. Van Leeuwen

    Pages 477-496

14. Metabolic Processing of Vasopressin in the Brain and Significance of Metabolites

    • J. Peter H. Burbach

    Pages 497-516

15. Vasopressin and Animal Behavior

    • Don M. Gash, James P. Herman, Garth J. Thomas

    Pages 517-547

16. Vasopressin and Human Behavior

    • Jellemer Jolles

    Pages 549-578

17. Aging of Rodent Vasopressin Systems

    • Paul F. Aravich, John R. Sladek Jr.

    Pages 579-610

18. Vasopressin in Relationship to Human Aging and Dementia

    • D. F. Swaab, E. Fliers, J. E. Hoogendijk

    Pages 611-625

19. Back Matter

    Pages 627-635

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The concept for Vasopressin: Principles and Properties originated during the sum­ mer of 1983. From reviewing the rich and diverse literature on vasopressin, it became evident that the rapid advancements in this field made it difficult to syn­ thesize the information gathered from divergent scientific disciplines into a coherent view of the biological role of vasopressin. We perceived the need for a series of critical reviews delineating this recent progress. Over the past decade, major advances have been made in studies of the anatomy, physiology, phar­ macology, molecular biology, and behavioral activities of vasopressin. This is, in no small measure, due to the finding that vasopressin can no longer be regarded solely as a neurohypophysial hormone. Our present knowledge is that vasopressin is synthesized in also has an axonal messenger role in the nervous system and of the brain, although the functions of vasopressin in these periph­ sites outside of vasopressin eral sites are not well understood. In order to prepare an overview concentrating on recent studies in vertebrates, authors were selected based on their expertise and asked to review their research area, including the work from other laboratories. It was our intent to provide an updated definitive reference which would complement and extend such past texts as Neurohypophysial Hor­ mones and Similar Polypeptides (Handbook of Experimental Pharmacology, Vol­ ume XXIII, 1968) and The Pituitary Gland and Its Neuroendocrine Control (Handbook of Physiology, Section 7: Volume IV, 1974).

• Peptide
• anatomy
• brain
• molecular biology
• nervous system
• physiology

• University of Rochester Medical Center, Rochester, USA

  Don Marshall Gash

• Netherlands Institute for Brain Research, Amsterdam, The Netherlands

  Gerard J. Boer

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