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Cancer, a compresensive treatise
cover

Etiology: Chemical and Physical Carcinogenesis

Authors: Becker, Frederick F.

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About this book

Six years ago when the first edition of this volume appeared as the first of the series, questions were posed in its preface that are as valid today as they were then. In that preface, I proposed the following challenges: (1) We must identify carcinogenic agents, and by an analysis of their "nature," e. g. , structure and physical characteristics, we may better understand their mechanism of action. (2) We must identify crucial interactions between these carcinogens and impor­ tant macromolecules within the cell, distinguishing those which relate to carcinogenesis from those which are extraneous. (3) We must examine the alterations of cell function induced by these reactions, for it is with an understanding of phenotypic variation that we may know why malignant cells escape from normal homeostatic control. (4) Last, and perhaps of greatest importance, we must define malignancy--define those charac­ teristics of cellular activity that permit the malignant cell to compete so effectively with the normal constituent, which ultimately Ieads to such destructive events. Although great strides have been made toward those goals, as evidenced by a number of new chapters and the new information gathered into others, and although the achievement of those goals sometimes appears but a tantalizing experiment away, none have been achieved. For example, several chapters indude descriptions of the progress that has been made toward the development of "quick assays.

Table of contents (19 chapters)

Table of contents (19 chapters)
  • Cytogenetics

    Pages 3-46

    Nowell, Peter C.

  • Genetics: Animal Tumors

    Pages 47-71

    Heston, W. E.

  • Genetic Influences in Human Tumors

    Pages 73-88

    Knudson, Alfred G., Jr.

  • Hormones as Etiological Agents in Neoplasia

    Pages 89-134

    Furth, Jacob

  • Pathogenesis of Plasmacytomas in Mice

    Pages 135-159

    Potter, Michael

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-1-4615-6598-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.99
price for USA in USD
  • ISBN 978-1-4615-6600-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Etiology: Chemical and Physical Carcinogenesis
Authors
Series Title
Cancer, a compresensive treatise
Copyright
1982
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-6598-7
DOI
10.1007/978-1-4615-6598-7
Softcover ISBN
978-1-4615-6600-7
Edition Number
1
Number of Pages
XXII, 714
Number of Illustrations
32 b/w illustrations
Topics