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  • © 2014

Genetic Damage in Human Spermatozoa

  • This book will cover all possible DNA damage in sperm
  • The book will also discuss its relation to fertility and transgenerational heritable effects
  • Chapter structure will include mechanisms of damage, consequences in reproduction, possibility to eliminate damage, and possible transgenerational heritable effects ?

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 791)

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eBook USD 129.00
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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xiii
  2. Structure of Chromatin in Spermatozoa

    • Lars Björndahl, Ulrik Kvist
    Pages 1-11
  3. Genomic Changes in Spermatozoa of the Aging Male

    • Chiara Chianese, Sara Brilli, Csilla Krausz
    Pages 13-26
  4. Chromosomal Aberrations and Aneuploidies of Spermatozoa

    • Paola Piomboni, Anita Stendardi, Laura Gambera
    Pages 27-52
  5. The Sperm Epigenome: Implications for the Embryo

    • John R. Gannon, Benjamin R. Emery, Timothy G. Jenkins, Douglas T. Carrell
    Pages 53-66
  6. Environmental Epigenetics and Effects on Male Fertility

    • Carlos Guerrero-Bosagna, Michael K. Skinner
    Pages 67-81
  7. Protamine Alterations in Human Spermatozoa

    • Meritxell Jodar, Rafael Oliva
    Pages 83-102
  8. Sperm DNA Fragmentation and Base Oxidation

    • Sheena E. M. Lewis
    Pages 103-116
  9. Iatrogenic Genetic Damage of Spermatozoa

    • Cristian O’Flaherty
    Pages 117-135
  10. Sperm Cryopreservation: Effects on Chromatin Structure

    • Donatella Paoli, Francesco Lombardo, Andrea Lenzi, Loredana Gandini
    Pages 137-150
  11. Sperm Selection: Effect on Sperm DNA Quality

    • Lodovico Parmegiani, Graçiela Estela Cognigni, Marco Filicori
    Pages 151-172
  12. Effect of Antioxidants on Sperm Genetic Damage

    • Yves Menezo, Don Evenson, Marc Cohen, Brian Dale
    Pages 173-189
  13. Erratum to: Structure of Chromatin in Spermatozoa

    • Lars Björndahl, Ulrik Kvist
    Pages E1-E1
  14. Back Matter

    Pages 191-195

About this book

There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

Editors and Affiliations

  • Department of Experimental and Clinical Biomedical Sciences, Florence, Italy

    Elisabetta Baldi, Monica Muratori

Bibliographic Information

  • Book Title: Genetic Damage in Human Spermatozoa

  • Editors: Elisabetta Baldi, Monica Muratori

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4614-7783-9

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2014

  • Hardcover ISBN: 978-1-4614-7782-2Published: 17 August 2013

  • Softcover ISBN: 978-1-4899-9471-4Published: 29 September 2015

  • eBook ISBN: 978-1-4614-7783-9Published: 16 August 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIII, 195

  • Topics: Human Genetics, Endocrinology, Reproductive Medicine

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access