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Advances in HIV-1 Assembly and Release

  • Book
  • © 2013
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Overview

Editors:
  1. Eric O. Freed

    1. HIV Drug Resistance Program, National Cancer Institute-Frederick, Frederick, USA

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  • Contains full-color illustrations
  • Incorporates tremendous advances in understanding of HIV-1 replication at the molecular level
  • Showcases a number of central topics related to HIV-1 assembly?

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-x
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  2. Structural Biology of HIV Assembly

    • Alex de Marco, Hans-Georg Kräusslich, John A. G. Briggs
    Pages 1-22
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  3. Cellular Trafficking Mechanisms in the Assembly and Release of HIV

    • Sebastian Giese, Mark Marsh
    Pages 23-53
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  4. Packaging of the HIV-1 RNA Genome

    • Jianbo Chen, Olga A. Nikolaitchik, Kari A. Dilley, Wei-Shau Hu
    Pages 55-73
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  5. Synthesis of Functional and Variable HIV-1 Envelope Glycoproteins

    • Paul R. Clapham
    Pages 75-122
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  6. HIV-1 Budding

    • Heinrich Göttlinger
    Pages 123-151
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  7. HIV-1 Maturation

    • Christopher Aiken, Peijun Zhang
    Pages 153-166
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  8. Cell-to-Cell Transmission of HIV

    • Luis M. Agosto, Peng Zhong, Walther Mothes
    Pages 167-184
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  9. Virus Assembly as a Target for Antiretroviral Therapy

    • Eric Barklis
    Pages 185-214
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  10. Back Matter

    Pages 215-221
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Keywords

About this book

​Over the past decade, enormous progress has been made in understanding the late events in the HIV replication cycle.  This has been made possible by major advances in cell biology, virology, and structural biology.  The field continues to move forward rapidly, with important new discoveries being reported on a regular basis.  The impact of this progress across a broad spectrum of biomedical research has been substantial.  The increase in basic knowledge in the areas of HIV assembly, release, and maturation has been accompanied by new possibilities for therapeutic intervention.The work includes topics relating to basic molecular biology, cell biology, and structural biology of HIV assembly, coupled with more applied ideas of how this basic information can inform the field of antiretroviral research.  The book covers all major topics pertaining to the late stages of HIV replication, with leaders in each area recruited to contribute chapters in their areas of expertise . The topics will be sufficiently focused to allow authors the opportunity to cover the latest developments in detail.​

Editors and Affiliations

  • HIV Drug Resistance Program, National Cancer Institute-Frederick, Frederick, USA

    Eric O. Freed

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