Obesity, Inflammation and Cancer
Editors: Dannenberg, Andrew J., Berger, Nathan A. (Eds.)
Free Preview- Provides the latest information implicating a link between obesity, inflammation and specific tumor types
- Describes innovative research on novel NSAIDS, omega 3 fatty acids, natural products, vascular targeting, caloric restriction and exercise in regards to cancer therapy
- Presents research connecting persistent inflammation to some of the comorbidities associated with cancer survivorship
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- About this book
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In addition to its metabolic and endocrinologic effects, obesity and adipose tissue have now been shown to be associated with low grade inflammation resulting in cellular and humoral inflammatory factors of which the latter may act by endocrine, paracrine and autocrine mechanisms. These inflammatory mediators have increasingly been suggested as contributing to the obesity link to carcinogenesis and cancer promotion.
This volume of Energy Balance and Cancer will focus on recent developments and cutting edge research pointing to inflammation and inflammatory factors as key mediators of this linkage. The volume first provides information on inflammation as an important link between obesity and insulin resistance, which is in itself linked to promotion of cancer through hyperinsulinemia. The volume then covers some of the most important mechanisms by which obesity leads to inflammation, including the novel inflammasome concept, alterations in chromatin structure, circulating inflammatory factors, unique cellular interactions between adipocytes and macrophages and the direct link of dietary fat to inflammation and cancer.
Overall, this volume will provide important insight to help understand how inflammation may help modulate the linkage between obesity and cancer and serve as a platform for developing future research in this area.
- Table of contents (16 chapters)
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Obesity, Inflammation, and Insulin Resistance
Pages 1-23
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Inflammasomes and Obesity
Pages 25-60
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Uncoupling Obesity from Cancer: Bromodomain Co-regulators That Control Inflammatory Networks
Pages 61-81
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Adipose Tissue Macrophages in Obesity, Inflammation, and Cancer
Pages 83-98
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Dietary Fats as Mediators of Obesity, Inflammation, and Colon Cancer
Pages 99-132
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Table of contents (16 chapters)
- Download Preface 1 PDF (40 KB)
- Download Sample pages 1 PDF (649.6 KB)
- Download Table of contents PDF (31 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Obesity, Inflammation and Cancer
- Editors
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- Andrew J. Dannenberg
- Nathan A. Berger
- Series Title
- Energy Balance and Cancer
- Series Volume
- 7
- Copyright
- 2013
- Publisher
- Springer-Verlag New York
- Copyright Holder
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4614-6819-6
- DOI
- 10.1007/978-1-4614-6819-6
- Hardcover ISBN
- 978-1-4614-6818-9
- Softcover ISBN
- 978-1-4899-9338-0
- Series ISSN
- 2199-2622
- Edition Number
- 1
- Number of Pages
- XIII, 433
- Topics
