Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines
Editors: Singh, Manmohan (Ed.)
Free Preview- Focus on the future of vaccines
- Addresss delivery systems for vaccines
- Explore the use of nanoparticles in vaccine delivery
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- About this book
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Development of new-generation vaccines is now more challenging than ever, as identifying, purifying and evaluating vaccine antigens is a complex undertaking. Most importantly, once the relevant antigens have been identified, key focus then shifts to the development of suitable delivery systems and formulations to achieve maximum in vivo potency with minimum potential side effects. These novel formulations—many of which will be nanoparticulates—can deliver the antigens to the desired site, to the relevant antigen presenting cells, and prevent systemic exposure of the immune potentiators. The proposed book will outline all the critical steps that need to be considered for successful development of various types of nanoparticulate delivery systems for vaccine antigens. These contributions from leading experts in the area of vaccine formulation and delivery systems will tie in what is the most current status, including clinical evaluations with these novel vaccine technologies.
- Table of contents (17 chapters)
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TLR7/8 Agonists as Vaccine Adjuvants
Pages 3-18
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Preclinical and Clinical Development of Synthetic iNKT-Cell Glycolipid Agonists as Vaccine Adjuvants
Pages 19-64
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Mucosal Vaccination: Opportunities and Challenges
Pages 65-80
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Oral Vaccination: Attenuated and Gene-Based
Pages 81-104
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Development of Biophysical Assays to Better Understand Adjuvanted Vaccine Formulation Potency and Stability
Pages 107-118
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Table of contents (17 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines
- Editors
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- Manmohan Singh
- Copyright
- 2013
- Publisher
- Springer US
- Copyright Holder
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4614-5380-2
- DOI
- 10.1007/978-1-4614-5380-2
- Hardcover ISBN
- 978-1-4614-5379-6
- Softcover ISBN
- 978-1-4899-9228-4
- Edition Number
- 1
- Number of Pages
- X, 370
- Topics
