- Unique focus in immunology
- A comprehensive volume on the subject
- Addressing a specific and neglected area of immunology
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- About this book
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In contrast to the substantial literature that focuses upon innate immune signaling in the gut, there is remarkably less known about the response of the airway to bacterial pathogens. The purpose of this book will be to review the current status of theunderstanding of the pathogenesis of acute bacterial pneumonia, slanted toward the mucosal immunology of these infections. It will describe, in general, the signaling cascades that control the proinflammatory response to bacterial infection in the lung. How innate immune signaling is orchestrated in response to specific common airway pathogens is addressed, targeting Staphylococus aureus (including MRSA), Streptococcus pneumoniae and Klebsiella pneumoniae. By describing the general immunological responses to conserved bacterial components and then detailing how specific organisms cause infection, this book provides a targeted but comprehensive review of this important topic.
- Table of contents (11 chapters)
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Alveolar Macrophages
Pages 1-48
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Lung Dendritic Cells and Pulmonary Defence Mechanisms to Bacteria
Pages 49-66
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CD4 T-Cell Immunity in the Lung
Pages 67-82
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Neutrophils in Acute Bacterial Pneumonia
Pages 83-124
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Toll-Like Receptors in the Airway Epithelium
Pages 125-138
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Table of contents (11 chapters)
- Download Sample pages 1 PDF (594.5 KB)
- Download Table of contents PDF (161.4 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Mucosal Immunology of Acute Bacterial Pneumonia
- Editors
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- Alice Prince
- Copyright
- 2013
- Publisher
- Springer-Verlag New York
- Copyright Holder
- Springer New York
- eBook ISBN
- 978-1-4614-5326-0
- DOI
- 10.1007/978-1-4614-5326-0
- Hardcover ISBN
- 978-1-4614-5325-3
- Softcover ISBN
- 978-1-4899-9035-8
- Edition Number
- 1
- Number of Pages
- X, 278
- Topics
