Regenerative Biology of the Spine and Spinal Cord

1. Front Matter

   Pages i-xxi

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2. Frontiers Of Spinal Cord And Spine Repair: Experimental Approaches for Repair of Spinal Cord Injury

   • Choya Yoon, Mark H. Tuszynski

   Pages 1-15

3. Stem Cell Based Strategies for Spinal Cord Injury Repair

   • Alexa Reeves, Hans S. Keirstead

   Pages 16-24

4. Strategies for Endogenous Spinal Cord Repair: HPMA Hydrogel to Recruit Migrating Endogenous Stem Cells

   • Araceli Espinosa-Jeffrey, Karlos Oregel, Laurent Wiggins, Remelyn Valera, Kathrin Bosnoyan, Chioma Agbo et al.

   Pages 25-52

5. Stem Cells and Spinal Cord Injury Repair

   • Soheila Karimi-Abdolrezaee, Eftekhar Eftekharpour

   Pages 53-73

6. Chronic Pain Following Spinal Cord Injury

   • Radi Masri, Asaf Keller

   Pages 74-88

7. Repair of Radiation Damage and Radiation Injury to the Spinal Cord

   • Timothy E. Schultheiss

   Pages 89-100

8. Malignancies of the Spinal Cord

   • J. Dawn Waters, Encarnacion Maria Navarro Peran, Joseph Ciacci

   Pages 101-113

9. Molecular Basis of Intervertebral Disc Degeneration

   • Dipika Gopal, Allen L. Ho, Amol Shah, John H. Chi

   Pages 114-133

10. Bioceramics for Osteogenesis, Molecular and Cellular Advances

    • Hande Demirkiran

    Pages 134-147

11. Cell-Based Therapies for Spinal Fusion

    • Ronke Olabisi

    Pages 148-173

12. Clinical Efficacy of Stem Cell Mediated Osteogenesis and Bioceramics for Bone Tissue Engineering

    • Josh Neman, Amanda Hambrecht, Cherie Cadry, Amir Goodarzi, Jonathan Youssefzadeh, Mike Y. Chen et al.

    Pages 174-187

13. Progenitor Cells: Role and Usage in Bone Tissue Engineering Approaches for Spinal Fusion

    • Lonnissa H. Nguyen, Vincent Duenas, Mike Y. Chen, Rahul Jandial

    Pages 188-210

14. Back Matter

    Pages 211-215

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Editors hope that Regenerative Biology of the Spine and Spinal Cord appeals to the nostalgic sentiments of investigators and intellectuals in that it can be held in hand and provide a broad survey of leading edge science. At the same time its chapters can be digitally acquired for those established in the field to refine particular knowledge interests or gaps. Most importantly, we ask the reader, whomever that may be, to peruse without prejudice as countless more chapters will have been written before total spinal regeneration is achieved.

• Biology
• Neurosurgery
• Regenerative
• Spinal cord
• Spine

• Division of Neurosurgery, City of Hope Cancer Center and Beckman Research Institute, Los Angeles, USA

  Rahul Jandial, Mike Y. Chen

Rahul Jandial, MD, PhD is an Assistant Professor in the Division of Neurosurgery, Department of Surgery at City of Hope Cancer Center and the Beckman Research Institute in Los Angeles, California. His clinical practice focuses on the surgical and medical care for patients with brain and spinal cancer. In the laboratory his team investigates molecular and cellular approaches for improving brain tumor treatment, as well as the use of stem cell biology for spinal regeneration. A prolific author and teacher, Jandial has authored/edited 8 books and over 40 papers. He lives with his wife Danielle and their sons Zain, Kai and Ronak.

Mike Y. Chen, MD, PhD is an Assistant Professor in the Division of Neurosurgery at City of Hope Cancer Center and the Beckman Research Institute in Los Angeles, California. He was educated at Pennsylvania State University (BS), Thomas Jefferson Medical School (MD), John Hopkins University (MS, Bioengineering), John Hopkins Hospital (internship), National Institutes of Health (fellowship), and Virginia Commonwealth University (neurosurgery residency and PhD). His clinical practice and laboratory research are aimed at developing novel surgical, molecular and genetic therapies for cancer of the brain and spine. He is married to a Southern belle, Valerie, and has two mischievous daughters.

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