Biochemical Roles of Eukaryotic Cell Surface Macromolecules

1. Front Matter

   Pages i-xvi

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2. Glycomics: An Overview of the Complex Glycocode

   • Garima Gupta, Avadhesha Surolia

   Pages 1-13

3. Structural Glycomic Approaches to Molecular Recognition Events on Cell Surfaces

   • Koichi Kato

   Pages 15-32

4. ISCSM2011 Chondroitin Sulfate E-type Structure at Tumor Cell Surface Is Involved in Experimental Metastasis

   • Kazuyuki Sugahara, Shuji Mizumoto

   Pages 33-45

5. Chondroitin Sulfate-Specific Novel Hydrolase in Human

   • Shuhei Yamada

   Pages 47-56

6. Identification of Endothelial Cell Surface Carbohydrate-Binding Receptors by Carbohydrate Ligand Mimicry Peptides

   • Michiko N. Fukuda

   Pages 57-66

7. Lysosomal Enzyme Sorting Receptors—Where Did They First Appear in the Animal Kingdom?

   • Suryanarayanaraju Vegiraju, Suresh Koduru, Siva Kumar Nadimpalli

   Pages 67-82

8. Endoplasmic Reticulum-Targeted Bcl-2 Inhibitable Mitochondrial Fragmentation Initiates ER Stress-Induced Cell Death

   • B. C. Bhavya, Deepa Indira, Mahendra Seervi, Jeena Joseph, Praveen K. Sobhan, Krupa Ann Mathew et al.

   Pages 83-95

9. Interactions Between Caveolin-1 and Sphingolipids, and Their Functional Relevance

   • Sandro Sonnino, Simona Prioni, Vanna Chigorno, Alessandro Prinetti

   Pages 97-115

10. Cell Membrane Repair Pathway Involves Sensing of Dynamics of Caveolae and Caspase-1

    • Saumya S. Srivastava, M. V. Krishnasastry

    Pages 117-129

11. Angiogenic Response of Endothelial Cells to Fibronectin

    • V. B. S. Kumar, R. I. Viji, M. S. Kiran, Perumana R. Sudhakaran

    Pages 131-151

12. Lactosylceramide Synthase as a Therapeutic Target to Mitigate Multiple Human Diseases in Animal Models

    • Subroto Chatterjee, Nezar Alsaeedi

    Pages 153-169

13. Advanced FRET Methodologies: Protein–Lipid Selectivity Detection and Quantification

    • Fábio Fernandes, Manuel Prieto, Luís M. S. Loura

    Pages 171-185

14. Mechanism of GPCR-Directed Autoantibodies in Diseases

    • Hamiyet Unal, Rajaganapathi Jagannathan, Sadashiva S. Karnik

    Pages 187-199

15. Role of Membrane Cholesterol in Leishmanial Infection

    • Amitabha Chattopadhyay, Md. Jafurulla

    Pages 201-213

16. How Intact Is the Basement Membrane? Role of MMPs

    • S. Asha Nair, Sankar Jagadeeshan, Ramachandran Indu, Perumana R. Sudhakaran, M. R. Pillai

    Pages 215-232

17. Apoptosis of Breast Cancer Cells: Modulation of Genes for Glycoconjugate Biosynthesis and Targeted Drug Delivery

    • Subhash Basu, Rui Ma, Joseph R. Moskal, Manju Basu, Sipra Banerjee

    Pages 233-255

18. Altered Expression of Sialidases in Human Cancer

    • Taeko Miyagi, K. Takahashi, S. Moriya, K. Hata, K. Yamamoto, T. Wada et al.

    Pages 257-267

19. Poly-ADP-Ribosylation of Vascular Endothelial Growth Factor and Its Implications on Angiogenesis

    • S. Binu, S. J. Soumya, V. B. S. Kumar, Perumana R. Sudhakaran

    Pages 269-278

20. Sphingolipid-Binding Domain in the Serotonin1A Receptor

    • Amitabha Chattopadhyay, Yamuna Devi Paila, Sandeep Shrivastava, Shrish Tiwari, Pushpendra Singh, Jacques Fantini

    Pages 279-293

Cell surface molecules are critically important in regulating cell structure and function. Recent advances on the functional role of cell surface molecules, particularly glycoconjugates are presented in this book. Comprising of 22 chapters from the 2011 International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules, it covers topics on the analysis of glycome, biophysical approaches to study cell surface molecules, glycoconjugate metabolism and its dysregulation, and molecular mechanisms involved in cell-cell and cell–matrix interaction.

• Proteomics
• carbohydrate chemistry

• Riverside Transit Campus, School of Biological Sciences, Central University of Kerala, Kasargod, India

  Perumana R. Sudhakaran

• National Institute of Immunology, New Delhi, India

  Avadhesha Surolia

Prof. Perumana R. Sudhakaran is currently the Dean of the School of Biological Sciences and Professor of Biochemistry, Central University of Kerala, Kasargod, India. His major area of research is cell extracellular matrix interaction and cell signaling. Prof. Avadesha Surolia is currently the Director of the National Institute of Immunology, New Delhi and a Professor of Molecular Biophysics at the Indian Institute of Science, Bangalore, India. His major areas of research include structure and function of lectins, orientation and dynamics of cell surface carbohydrate receptors, protein folding and quality control in the endoplasmic reticulum.

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