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  • Book
  • © 2012

Protein Dimerization and Oligomerization in Biology

  • Covers many aspects of hetero-oligomerization
  • Gives comprehensive overview of the contributions of protein dimer and oligomer formation to nucleic acid binding
  • Provides an overview of repeat proteins

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 747)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xiv
  2. Dimers, Oligomers, Everywhere

    • Jacqueline M. Matthews, Margaret Sunde
    Pages 1-18
  3. The Detection and Quantitation of Protein Oligomerization

    • David A. Gell, Richard P. Grant, Joel P. Mackay
    Pages 19-41
  4. Death by Caspase Dimerization

    • Sarah H. MacKenzie, A. Clay Clark
    Pages 55-73
  5. The Relationship between Oligomeric State and Protein Function

    • Michael D. W. Griffin, Juliet A. Gerrard
    Pages 74-90
  6. Oligonucleotide Binding Proteins

    • Jackie Wilce, Julian Vivian, Matthew Wilce
    Pages 91-104
  7. Homo- and Heterodimerization in Transcriptional Regulation

    • Alister P. W. Funnell, Merlin Crossley
    Pages 105-121
  8. Oligomerization at the Membrane

    • Oliver B. Clarke, Jacqueline M. Gulbis
    Pages 122-136
  9. Implications of 3D Domain Swapping for Protein Folding, Misfolding and Function

    • Frederic Rousseau, Joost Schymkowitz, Laura S. Itzhaki
    Pages 137-152
  10. From Artificial Antibodies to Nanosprings

    • Laura S. Itzhaki, Alan R. Lowe
    Pages 153-166
  11. Back Matter

    Pages 167-170

About this book

This volume has a strong focus on homo-oligomerization, which is surprisingly common. However, protein function is so often linked to both homo- and hetero-oligomerization and many heterologous interactions likely evolved from homologous interaction, so this volume also covers many aspects of hetero-oligomerization.

Editors and Affiliations

  • School of Molecular Bioscience, University of Sydney, Sydney, Australia

    Jacqueline M. Matthews

About the editor

Jacqueline (Jacqui) Matthews is currently a Senior Research Fellow of the National Health and Medical Research Council of Australia, and the Professor of Protein Chemistry at the University of Sydney. Her research focuses on regulatory proteins involved in development and disease, and in particular on protein-protein and protein-DNA interactions within transcription factor complexes. Dr. Matthews received her undergraduate training (BSc Hons) in chemistry and biochemistry at the University of New South Wales in Sydney, Australia, and a PhD in biological chemistry (for work on protein folding under the supervision of Sir Professor Alan Fersht) from the University of Cambridge, UK. She is currently President of the Sydney Protein Group, a member of the Executive Council of the Protein Society and a member of the Australian Society for Biochemistry and Molecular Biology, and Australian Biophysical Society.

Bibliographic Information

  • Book Title: Protein Dimerization and Oligomerization in Biology

  • Editors: Jacqueline M. Matthews

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4614-3229-6

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2012

  • Hardcover ISBN: 978-1-4614-3228-9Published: 30 May 2012

  • Softcover ISBN: 978-1-4939-4449-1Published: 23 August 2016

  • eBook ISBN: 978-1-4614-3229-6Published: 04 September 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIV, 170

  • Topics: Biomedicine general, Molecular Medicine

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access