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Multifunctional Nanoparticles for Drug Delivery Applications

Imaging, Targeting, and Delivery

  • Book
  • © 2012

Overview

Editors:
  1. Sonke Svenson

    1. Drug Delivery Solutions LLC, Arlington, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Robert K. Prud'homme

    1. Princeton University, Princeton, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • First monograph to provide overview of multifunctional nanoparticles
  • An invaluable resource for government regulatory agencies, teachers of advanced courses, and advanced students alike
  • Globally respected contributors provide insight into cutting edge research, as well as commentary on the benefits and challenges of the field
  • Includes supplementary material: sn.pub/extras

Part of the book series: Nanostructure Science and Technology (NST)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-x
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  2. Introduction: Benefits and Challenges for Multifunctional Nanoparticles in Medicine

    • Robert K. Prud’homme, Sonke Svenson
    Pages 1-5

  3. Targeting and Drug Delivery

    1. Front Matter

      Pages 7-7
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    2. Nanoparticles for Targeted and Temporally Controlled Drug Delivery

      • Archana Swami, Jinjun Shi, Suresh Gadde, Alexander R. Votruba, Nagesh Kolishetti, Omid C. Farokhzad
      Pages 9-29

    3. Development and Application of Anticancer Nanomedicine

      • Rong Tong, Li Tang, Jianjun Cheng
      Pages 31-46

    4. Macrophage-Targeted Nanoparticle Delivery Systems

      • Shardool Jain, Mansoor Amiji
      Pages 47-83

    5. Paclitaxel-Triazine Dendrimer Constructs: Efficacy, Toxicity, and Characterization

      • Eric E. Simanek, Jongdoo Lim
      Pages 85-100

  4. Dual or Multiple Drug Delivery (Combination Therapy)

    1. Front Matter

      Pages 101-101
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  5. Dual or Multiple Drug Delivery Combination Therapy

    1. Versatile Fixed-Ratio Drug Combination Delivery Using Hydrophobic Prodrug Nanoparticles

      • Barry D. Liboiron, Paul G. Tardi, Lawrence D. Mayer
      Pages 103-132

    2. Polymeric Micelles for Multiple-Drug Delivery

      • Glen S. Kwon
      Pages 133-152

  6. Targeting and Imaging

    1. Front Matter

      Pages 153-153
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    2. Multifunctional Nanoparticles for Target-Specific Imaging and Therapy

      • Anita Gianella, Joanna C. Read, David P. Cormode, Zahi A. Fayad, Willem J. M. Mulder
      Pages 155-171

    3. Polymer-Modified Nanoparticles as Targeted MR Imaging Agents

      • Stephen G. Boyes, Misty D. Rowe, Chia-Chih Chang, Talia J. Sanchez, Wilasinee Hatakeyama, Natalie J. Serkova et al.
      Pages 173-198

  7. Diagnostic and Therapy (“Theranostics”)

    1. Front Matter

      Pages 199-199
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  8. Diagnostic and Therapy Theranostics

    1. Injectable Multistage Nanovectors for Enhancing Imaging Contrast and Directed Therapy

      • Biana Godin, Rita E. Serda, Xuewu Liu, Mauro Ferrari
      Pages 201-223

    2. Targeted, Multifunctional Hydrogel Nanoparticles for Imaging and Treatment of Cancer

      • Yong-Eun Koo Lee, Raoul Kopelman
      Pages 225-255

    3. Theranostic Polymeric Micelles for Cancer Imaging and Therapy

      • Gang Huang, Chalermchai Khemtong, Erik A. Bey, David A. Boothman, Baran D. Sumer, Jinming Gao
      Pages 257-276

    4. Multifunctional Nanoparticles for Personalized Medicine

      • Benjamin T. Roller, Kathleen M. McNeeley, Ravi V. Bellamkonda
      Pages 277-293

    5. Dendrimer-Based Nanoparticle Therapies: Can Uniform Multifunctional Therapeutics Be Made with Current Chemical Approaches?

      • Douglas G. Mullen, Daniel Q. McNerny, Mark M. Banaszak Holl, James R. Baker Jr.
      Pages 295-313

    6. Multivalent Dendritic Architectures for Theranostics

      • Stephanie Reichert, Marcelo Calderón, Kai Licha, Rainer Haag
      Pages 315-344
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Keywords

About this book

This book clearly demonstrates the progression of nanoparticle therapeutics from basic research to applications. This book, unlike others covering nanoparticles used in medical applications, presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy.

Editors and Affiliations

  • Drug Delivery Solutions LLC, Arlington, USA

    Sonke Svenson

  • Princeton University, Princeton, USA

    Robert K. Prud'homme

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