Skip to main content
SpringerLink
Log in

Insulin-like Growth Factors and Cancer

From Basic Biology to Therapeutics

  • Book
  • © 2012

Overview

Editors:
  1. Derek LeRoith

    1. , Department of Medicine, Mount Sinai School of Medicine, NEW YORK, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Comprehensive look at the history of targeted therapies in cancer
  • Edited by a recognized expert in IGF Systems and cancer
  • Discusses the successes and failures of targeted therapies and cancer
  • Includes supplementary material: sn.pub/extras

Part of the book series: Cancer Drug Discovery and Development (CDD&D)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (14 chapters)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Epidemiology of IGF-1 and Cancer

    • Katharina Nimptsch, Edward Giovannucci
    Pages 1-24

  3. Aging and Cancer: The IGF-I Connection

    • Kalina Biernacka, Claire Perks, Jeff Holly
    Pages 25-36

  4. Obesity, Type 2 Diabetes and Cancer

    • Rosalyn D. Ferguson, Derek LeRoith
    Pages 37-72

  5. IGF System and Breast Cancer

    • Marc A. Becker, Douglas Yee
    Pages 73-84

  6. The Role of Insulin-Like Growth Factor Signaling in Prostate Cancer Development and Progression

    • Bruce Montgomery, James Dean, Stephen Plymate
    Pages 85-103

  7. IGF-1 Cellular Action and its Relationship to Cancer: Evidence from in Vitro and in Vivo Studies

    • Rosalyn D. Ferguson, Nyosha Alikhani, Archana Vijayakumar, Yvonne Fierz, Dara Cannata, Shoshana Yakar
    Pages 105-146

  8. Insulin-Like Growth Factor Signaling in Pediatric Sarcomas

    • Xiaolin Wan, Su Young Kim, Lee J. Helman
    Pages 147-158

  9. Cancer Genes, Tumor Suppressors, and Regulation of IGF1-R Gene Expression in Cancer

    • Haim Werner, Zohar Attias-Geva, Itay Bentov, Rive Sarfstein, Hagit Schayek, Doron Weinstein et al.
    Pages 159-177

  10. Mouse Models of IGF-1R and Cancer

    • Craig I. Campbell, James J. Petrik, Roger A. Moorehead
    Pages 179-191

  11. Targeting the Insulin-Like Growth Factor-I Receptor in Cancer Therapy

    • David R. Clemmons
    Pages 193-213

  12. Targeting Insulin-Like Growth Factor Receptor 1 (IGF-1R) and Insulin Receptor Signaling by Tyrosine Kinase Inhibitors in Cancer

    • Joan M. Carboni, Mark Wittman, Fei Huang
    Pages 215-229

  13. Calories and Cancer: The Role of Insulin-Like Growth Factor-1

    • Stephen D. Hursting, Sarah D. Smith, Alison E. Harvey, Laura M. Lashinger
    Pages 231-243

  14. Cancer Cell Metabolism

    • Akash Patnaik, Jason W. Locasale, Lewis C. Cantley
    Pages 245-261

  15. Overlaps Between the Insulin and IGF-I Receptor and Cancer

    • Antonino Belfiore, Roberta Malaguarnera
    Pages 263-278

  16. Back Matter

    Pages 279-284
    Download chapter PDF
Back to top

Keywords

About this book

The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.

Editors and Affiliations

  • , Department of Medicine, Mount Sinai School of Medicine, NEW YORK, USA

    Derek LeRoith

Bibliographic Information

  • Book Title: Insulin-like Growth Factors and Cancer

  • Book Subtitle: From Basic Biology to Therapeutics

  • Editors: Derek LeRoith

  • Series Title: Cancer Drug Discovery and Development

  • DOI: https://doi.org/10.1007/978-1-4614-0598-6

  • Publisher: Humana New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-4614-0597-9Published: 15 September 2011

  • Softcover ISBN: 978-1-4614-2962-3Published: 24 October 2013

  • eBook ISBN: 978-1-4614-0598-6Published: 18 September 2011

  • Series ISSN: 2196-9906

  • Series E-ISSN: 2196-9914

  • Edition Number: 1

  • Number of Pages: XII, 284

  • Topics: Cancer Research, Pharmacology/Toxicology

Publish with us

Policies and ethics

Back to top

Search

Navigation