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Advances in Experimental Medicine and Biology

Toward Anti-Adhesion Therapy for Microbial Diseases

Editors: Kahane, Itzahak, Ofek, Itzhak (Eds.)

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  • ISBN 978-1-4613-0415-9
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About this book

The emergence of pathogens resistant to conventional antimicrobial agents has forced us to intensify the efforts in search for new approaches to prevent infectious diseases. Such a direction was indicated in studies over the last two decades showing that adhesion of pathogens, primarily via glycoconjugate or protein receptors of the host tissue, is crucial for the infectious process. Moreover, it was found that infection can be prevented by blocking adhesion of the pathogen to mucosal surfaces of the host. The various aspects of interference with the process of microbial adhesion as a way of preventing diseases were the subject of the Bat-Sheva Seminar, "Towards Anti-Adhesion Therapy of Microbial Infectious Diseases," held in Zichron Yaakov, Israel, February 25 to March I, 1996. A major aim of the Bat-Sheva de Rothschild Foundation for the Advancement of Science in Israel, which sponsors a series of seminars, ours among them, is to provide the necessary tools and settings for international forums and exposure of young scientists and promising students to the state of the art of the field. This goal has been achieved during the week's discussions, and its major aspects are presented in this compendium. The seminar's participants, as well as the readers of this book, thank the founder and Foundation for their support. This book includes the major themes of this rapidly growing area. However, by no means do we intend to cover every bit and piece in it. The book's first section deals with the lectin-sugar interactions and their inhibitors.

Table of contents (30 chapters)

Table of contents (30 chapters)
  • Carbohydrate—Lectin Interactions in Infectious Disease

    Pages 1-8

    Sharon, Nathan

  • Anti-Adhesion and Diagnostic Strategies for Oro-Intestinal Bacterial Pathogens

    Pages 9-24

    Strömberg, Nicklas (et al.)

  • The GALα1–4GAL-Binding Adhesin of Streptococcus Suis, A Gram-Positive Meningitis-Associated Bacterium

    Pages 25-34

    Haataja, Sauli (et al.)

  • Development of Anti-Adhesion Carbohydrate Drugs for Clinical Use

    Pages 35-38

    Zopf, D. (et al.)

  • Towards Anti- Pseudomonas Aeruginosa Adhesion Therapy

    Pages 39-50

    Gilboa-Garber, Nechama

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4613-0415-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $149.00
price for USA in USD
  • ISBN 978-1-4613-8042-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Toward Anti-Adhesion Therapy for Microbial Diseases
Editors
  • Itzahak Kahane
  • Itzhak Ofek
Series Title
Advances in Experimental Medicine and Biology
Series Volume
408
Copyright
1996
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4613-0415-9
DOI
10.1007/978-1-4613-0415-9
Softcover ISBN
978-1-4613-8042-9
Series ISSN
0065-2598
Edition Number
1
Number of Pages
297
Topics