Advances in Experimental Medicine and Biology

Purine and Pyrimidine Metabolism in Man IX

Editors: Griesmacher, Andrea, Chiba, Peter, Müller, Mathias M. (Eds.)

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About this book

th th This volume comprizes articles presented at the joint IX International and 6 Euro­ pean Symposium on Purine and Pyrimidine Metabolism in Man held in Gmunden, Austria, June 1 through 7, 1997. Since the first of this series of meetings was held in Israel in 1973, conventions were organized every three years in different parts of the world including the USA, Japan, and Europe. The different aspects of purine and pyrimidine metabolism bring together re­ searchers working in molecular genetics, biochemical pharmacology, biochemistry, devel­ opmental biology, immunology, epidemiology and the clinics. Oriented research in the field has been seminal for the development of potent anticancer and antiviral drugs. As the number of genes which are cloned, grows, the understanding of metabolism is increas­ ingly enlarged and might provide leads to further improve therapeutic concepts and to bet­ ter understand mechanisms responsible for the development of resistance against these drugs. In certain diseases purine and pyrimidine analogs represent not only the drugs of choice but in fact are the sole therapeutic alternative at present. The field has also taken an early lead in attempting to correct inborn errors of purine and pyrimidine metabolism by gene therapy. The organization of this meeting involved a large number of people who dedicated their time in an effort to make this symposium a success. We thank the Abstract Review Committee, the International Advisory Board and in particular the Symposium Secretariat for doing a wonderful job.

Table of contents (166 chapters)

Table of contents (166 chapters)
  • Gout New Questions for an Ancient Disease

    Pages 1-5

    Puig, Juan G. (et al.)

  • Efficacy of Allopurinol in Ameliorating the Progressive Renal Disease in Familial Juvenile Hyperuricaemic Nephropathy (FJHN)

    Pages 7-11

    McBride, M. B. (et al.)

  • Optimal Range of Serum Urate Concentrations to Minimize Risk of Gouty Attacks During Anti-Hyperuricemic Treatment

    Pages 13-18

    Yamanaka, Hisashi (et al.)

  • How Should we Treat Tophaceous Gout in Patients with Allopurinol Hypersensitivity?

    Pages 19-23

    Grahame, R. (et al.)

  • The Spectrum of HGPRT Deficiency

    Pages 25-29

    Puig, Juan G. (et al.)

Buy this book

eBook $59.99
price for USA in USD
  • ISBN 978-1-4615-5381-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $79.99
price for USA in USD
  • ISBN 978-1-4613-7456-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Purine and Pyrimidine Metabolism in Man IX
Editors
  • Andrea Griesmacher
  • Peter Chiba
  • Mathias M. Müller
Series Title
Advances in Experimental Medicine and Biology
Series Volume
431
Copyright
1998
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4615-5381-6
DOI
10.1007/978-1-4615-5381-6
Softcover ISBN
978-1-4613-7456-5
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XXV, 866
Topics