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Advances in Experimental Medicine and Biology

Resolving the Antibiotic Paradox

Progress in Understanding Drug Resistance and Development of New Antibiotics

Editors: Rosen, Barry P., Mobashery, Shahriar (Eds.)

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About this book

Antibiotic resistance, once a term appreciated only by microbiologists, has become a common topic in the popular press. Stuart Levy, one of the contributors to this collection, bears some of the responsibility for increasing public awareness with the publication of his book "The Antibiotic Paradox" in 1992: Misuse of antibiotics resulting in increased bacterial resistance had previously been recognized in the infectious disease community. However, Dr. Levy's eloquent public warning about the shrinking efficacy of our antibi­ otic armamentarium served to alert the lay person to the potential consequences of this de­ mise in useful therapy. Because of the proliferation of diverse antibiotic classes with increasing potency and broader activity spectra, it had been assumed that any ordinary bacterial infection could be eradicated with the proper selection of drug. However, it has become evident that we are surrounded by resistant bacteria, many of which were introduced unwittingly into our en­ vironment through the unnecessary use of antibiotics. When it became evident that a number of people were returning for multiple visits to their family physicians for persist­ ent ear infections or non-responsive bronchitis, questions were raised about the antibiotic treatments that were being prescribed. Bacteria resistant to common antibiotic regimens were being isolated more frequently, often as organisms classified as "multi-resistant" with decreased susceptibilities to two or more structural classes of agents. Nosocomial spread of these resistances was aided by the transmission of plasmid-mediated resistance factors between species.

Table of contents (14 chapters)

Table of contents (14 chapters)

Buy this book

eBook $84.99
price for USA in USD
  • ISBN 978-1-4615-4897-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.99
price for USA in USD
  • ISBN 978-1-4613-7220-2
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Resolving the Antibiotic Paradox
Book Subtitle
Progress in Understanding Drug Resistance and Development of New Antibiotics
Editors
  • Barry P. Rosen
  • Shahriar Mobashery
Series Title
Advances in Experimental Medicine and Biology
Series Volume
456
Copyright
1998
Publisher
Springer US
Copyright Holder
Kluwer Academic/Plenum Publishers, New York
eBook ISBN
978-1-4615-4897-3
DOI
10.1007/978-1-4615-4897-3
Softcover ISBN
978-1-4613-7220-2
Series ISSN
0065-2598
Edition Number
1
Number of Pages
X, 293
Topics

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