Fibrinogen, Thrombosis, Coagulation, and Fibrinolysis

1. Front Matter

   Pages i-x

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2. Fibrinogen and Fibrin

   1. Native Fibrin Gel Networks and Factors Influencing their Formation in Health and Disease

      • B. Blombäck, D. Banerjee, K. Carlsson, A. Hamsten, B. Hessel, R. Procyk et al.

      Pages 1-23

   2. The Structure and Evolution of Vertebrate Fibrinogen: A Comparison of the Lamprey and Mammalian Proteins

      • Russell F. Doolittle

      Pages 25-37

   3. Nucleotide Sequences of the Three Genes Coding for Human Fibrinogen

      • Dominic W. Chung, Jeff E. Harris, Earl W. Davie

      Pages 39-48

   4. On the Identity of Fibrin(ogen) Oligomers Appearing during Fibrin Polymerization

      • Agnes Henschen

      Pages 49-53

   5. Immunochemical Studies of Aα Chain Crosslinking

      • Joan H. Sobel, Robert E. Canfield

      Pages 55-61

   6. Abnormal Fibrinogens with Two Structural Defects

      • Michio Matsuda, Shigeharu Terukina, Nobuhiko Yoshida, Kensuke Yamazumi, Hisato Maekawa

      Pages 63-72

   7. Electrophoretic Characterizations of Cross-Linked Fibrinogen Derivatives in Blood and Vascular Tissue by Zonal Immobilization on Glyoxyl Agarose

      • John R. Shainoff, Rafael Valenzuela, Robert Graor, David A. Urbanic, Patricia M. DiBello

      Pages 73-81

   8. Studies on the Localization and Accessibility of Sites in Fibrin which are Involved in the Acceleration of the Activation of Plasminogen by Tissue-Type Plasminogen Activator

      • W. Nieuwenhuizen, W. J. G. Schielen, O. Yonekawa, G. I. Tesser, M. Voskuilen

      Pages 83-91

3. Coagulation and Fibrinolysis

   1. Coagulation

      1. Prothrombinase: Recognition and Developments

         • Walter H. Seegers

         Pages 93-96

      2. The Initiation of the Tissue Factor Dependent Pathway of Blood Coagulation

         • Samuel I. Rapaport

         Pages 97-103

      3. Interactions between the Contact System, Neutrophils and Fibrinogen

         • Robert W. Colman

         Pages 105-120

      4. A New Trisaccharide Sugar Chain Linked to a Serine Residue in the First EGF-Like Domain of Clotting Factors VII and IX and Protein Z

         • Sadaaki Iwanaga, Hitoshi Nishimura, Shun-ichiro Kawabata, Walter Kisiel, Sumihiro Hase, Tokuji Ikenaka

         Pages 121-131

      5. Multiple Epitope Specificity of Monoclonal Antibodies to a Single Synthetic Peptide: Use in the Characterization of the GP IIb-IIIa Binding Domain of Von Willebrand Factor

         • Shlomo A. Berliner, Richard A. Houghten, James R. Roberts, Zaverio M. Ruggeri

         Pages 133-144

      6. Factor VII and Dietary Fat Intake

         • G. J. Miller, J. C. Martin, K. A. Mitropoulos, J. K. Cruickshank

         Pages 145-149

      7. Characterization of Snake Venom Principles Affecting Blood Coagulation and Platelet Aggregation

         • Chaoho Ouyang, Che-Ming Teng, Tur-Fu Huang

         Pages 151-163

      8. Thrombin-Like Venom Enzymes: Structure and Function

         • Hubert Pirkle, Ida Theodor

         Pages 165-175

      9. Thrombin Inhibition by Synthetic Hirudin Peptides

         • John M. Maraganore, John W. Fenton II

         Pages 177-183

   2. Fibrinolysis

      1. Effects of Structural Modifications on the Properties of Tissue Plasminogen Activator (tPA)

         • Per Wallén, Xiang-Fei Cheng, Per-Ingvar Ohlsson

         Pages 185-194

      2. Molecular Genetics of Alpha 2 Plasmin Inhibitor

         • Nobuo Aoki

         Pages 195-200

The International Scientific Symposium on Fibrinogen, Thrombosis, Coagulation, and Fibrinolysis was held in Academia Sinica, Taipei, Taiwan, Republic of China, on August 30 - September 1, 1989. This Symposium has provided a forum for the free exchange of information in this important and rapidly advancing research field. This proceedings volume provides a published record of 46 papers presented at the Symposium. The sponsors have exerted no influence on the scientific opinions or positions of the participants in the Symposium. It is hoped that this Symposium will stimulate further worldwide cooperation and collaboration in these vital fields for the benefit of all human kind. This volume is composed of four parts. The first part consists of 8 papers on Fibrinogen and Fibrin: Biochemistry, Molecular Biology, and Physiology. The second part contains 16 papers on Coagulation and Fibrinolysis: Biochemistry, Molecular Biology, and Physiology. The third part has 10 papers on Cardiovascular Cell Biology: Biochemistry, Molecular Biology, and Physiology. The fourth part comprises 12 papers on Clinical Studies of the Cardiovascular System: Thrombotic and Bleeding Disorders and Thrombolytic Therapy. The Author Index with addresses of all contributors and the Subject Index of all 46 papers are arranged at the end of this volume.

• biochemistry
• biology
• cardiovascular system
• cell biology
• molecular biology
• physiology
• research
• thrombosis

• Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, Republic of China

  Chung Yuan Liu

• University of California, San Diego, La Jolla, USA

  Shu Chien

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