Save today: Get 40% off Social Science print books or $30 off eBooks in Engineering & Energy!

Advances in Experimental Medicine and Biology

Innovations in Antiviral Development and the Detection of Virus Infections

Editors: Block, T., Crowell, R., Dennison, M., Jungkind, D.L., Walsh, L.R. (Eds.)

Free Preview

Buy this book

eBook $59.99
price for USA in USD (gross)
  • ISBN 978-1-4615-3462-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $79.99
price for USA in USD
  • ISBN 978-1-4613-6533-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

THE ERA OF ANTIVIRALS Introduction Although there are more than one hundred medically useful antibiotics and fungicides, there are only seven compounds licensed for use as antiviral agents, in the USA. Some of these (acyclovir and ganciclovir) are actually derivatives of each other, making the number of new discoveries even smaller. Moreover, most of these agents are of only limited therapeutic value and have substantial toxicity. It has been more than 100 years ago since Pasteur studied rabies virus (2) and Rous (4) showed that a small filterable agent (not bacteria) caused disease (sarcoma) in chickens. It was nearly 100 years ago that yellow fever virus, the first recognized human pathogenic virus, was unambiguously associated with disease (3). Enteroviruses were cultured for the first time nearly 50 years ago (1). Why then has effective chemotherapy against viruses lagged behind that of other microorganisms? Viruses are often difficult to grow and image. However, with the dynamic advances in molecular biology and increased sophistication in tissue culture, the field of virology has blossomed and resulted in improved methods for detection of virus infection. The use of viruses as models of gene regulation and replication has also resulted in a massive accumulation of information.

Table of contents (21 chapters)

Table of contents (21 chapters)

Buy this book

eBook $59.99
price for USA in USD (gross)
  • ISBN 978-1-4615-3462-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $79.99
price for USA in USD
  • ISBN 978-1-4613-6533-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Innovations in Antiviral Development and the Detection of Virus Infections
Editors
  • Timothy Block
  • Richard Crowell
  • Mark Dennison
  • Donald L. Jungkind
  • Lori R. Walsh
Series Title
Advances in Experimental Medicine and Biology
Series Volume
312
Copyright
1992
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-3462-4
DOI
10.1007/978-1-4615-3462-4
Softcover ISBN
978-1-4613-6533-4
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XVII, 218
Topics