Advances in Experimental Medicine and Biology

Prostate Cancer and Bone Metastasis

Editors: Karr, James P., Yamanaka, Hidetoshi (Eds.)

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About this book

The biology of solid tumor metastasis has been the subject of significant scientific and clinical interest for years and while experimental evidence reveals that metastasis is not solely a random event, very little is known about the biology of metastasis originating from prostate cancer. This is in spite of the fact that the majority of prostate cancer patients die with metastatic lesions to the bone. Progress in understanding this most important aspect of prostate cancer has been hampered by the lack of suitable animal models and an inability to accurately quantify bone metastases and their responses to therapy. Over the past decade, scientists in Japan and the United States have steadily advanced our understanding of the cellular, molecular and immunologic biology of primary and disseminated prostate cancer. It is this body of new information, combined with advances in imaging techniques and prostate cancer tumor markers, that prompted the need for an in-depth assessment of bone metastasis of prostate cancer. Accordingly, on December 12, 1990, a group of basic and clinical investigators from Japan and the United States convened in Gotenba, Japan, to hold the first conference devoted solely to the basic biology and clinical aspects of bone metastases originating from prostate cancer. The cross-fertilization of ideas that was fostered through in-depth discussion of technological advances among various basic and clinical disciplines not only further advanced our understanding of prostate metastases to the bone, but suggested approaches for precise quantitative assessment of these lesions and their treatment.

Table of contents (33 chapters)

Table of contents (33 chapters)
  • Clinical Dilemmas and Problems in Assessing Prostatic Metastasis to Bone: The Scientific Challenge

    Grayhack, John T. (et al.)

    Pages 1-5

  • Comparative Study of Prostatic Carcinoma Bone Metastasis among Japanese in Japan and Japanese Americans and Whites in Hawaii

    Shiraishi, Taizo (et al.)

    Pages 7-16

  • Prostate Cancer in the United States and Japan

    Karr, James P.

    Pages 17-28

  • Analysis of Survival of Prostate Cancer Patients in Japan and the USA

    Imai, Kyoichi (et al.)

    Pages 29-38

  • The Cellular Basis for Prostate Cancer Metastasis

    Zetter, Bruce R. (et al.)

    Pages 39-43

Buy this book

eBook $59.99
price for USA in USD (gross)
  • ISBN 978-1-4615-3398-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $79.99
price for USA in USD
  • ISBN 978-1-4613-6501-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Prostate Cancer and Bone Metastasis
Editors
  • James P. Karr
  • Hidetoshi Yamanaka
Series Title
Advances in Experimental Medicine and Biology
Series Volume
324
Copyright
1992
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-3398-6
DOI
10.1007/978-1-4615-3398-6
Softcover ISBN
978-1-4613-6501-3
Series ISSN
0065-2598
Edition Number
1
Number of Pages
IX, 323
Topics