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Advances in Experimental Medicine and Biology

The Underlying Molecular, Cellular and Immunological Factors in Cancer and Aging

Editors: Yang, Stringer Sue (Ed.)

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About this book

Background Cancer is a variety of malignancies generally associated with aging. As the overall health technology and health care delivery improved with the advances made in medicine and science in the United States, the life expectancy of the population also increased. The average life expectancy in the U. S. A. has increased from 49 years at the end of 1900 to 75 years today in 1990 (1-3). The population of 65 years and older that constituted 25. 5 million or 11. 3% of the total U. S. population in 1980(4) has now increased to 31. 1 million or 12. 5% of the population according to the 1990(5) census. As cancer diagnosis and treatment have improved, cancer mortality among patients under 55 has been significantly reduced within recent years *1; however, cancer incidence under 55 is still increasing at about 0. 4% per year (as compared to 1. 0% for all ages or 0. 6% for < 65) according to the 1990 review of the 15 year trends in the Cancer Statistics Review 1973-1987, published by the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute (NCI). In contrast, both cancer incidence and mortality have been increasing among the population 65 and over*2 at a rate of 1. 4% and 1. 0% respectively per year between 1973-1987(6).

Table of contents (23 chapters)

Table of contents (23 chapters)
  • Aging, Comorbidity, and Breast Cancer Survival: An Epidemiologic View

    Pages 1-11

    Satariano, William A.

  • Squamous Cell Cancer of the Cervix, Immune Senescence and HPV: Is Cervical Cancer an Age-Related Neoplasm ?

    Pages 13-26

    Mandelblatt, Jeanne

  • Genetic and Molecular Basis for Cellular Senescence

    Pages 27-43

    Barrett, J. Carl (et al.)

  • A Single Gene Change Can Extend Yeast Life Span: The Role of RAS in Cellular Senescence

    Pages 45-53

    Jazwinski, S. Michal (et al.)

  • A Comparison of the Properties of Human P53 Mutant Alleles

    Pages 55-65

    Quartin, Robin S. (et al.)

Buy this book

eBook $59.99
price for USA in USD (gross)
  • ISBN 978-1-4615-2926-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $79.99
price for USA in USD
  • ISBN 978-1-4613-6270-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Underlying Molecular, Cellular and Immunological Factors in Cancer and Aging
Editors
  • Stringer Sue Yang
Series Title
Advances in Experimental Medicine and Biology
Series Volume
330
Copyright
1993
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-2926-2
DOI
10.1007/978-1-4615-2926-2
Softcover ISBN
978-1-4613-6270-8
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIV, 336
Topics