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Advances in Experimental Medicine and Biology

Dendritic Cells in Fundamental and Clinical Immunology

Volume 2

Editors: Banchereau, Jacques, Schmitt, Daniel (Eds.)

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About this book

These Proceedings contain the contributions of the partIcIpants of the Third International Symposium on Dendritic Cells that was held in Annecy, France, from June 19 to June 24, 1994. This symposium represented a follow-up of the first and second international symposia that were held in Japan in 1990 and in the Netherlands in 1992. Dendritic cells are antigen-presenting cells, and are found in all tissues and organs of the body. They can be classified into: (1) interstitial dendritic cells of the heart, kidney, gut, and lung;(2) Langerhans cells in the skin and mucous membranes; (3) interdigitating dendritic cells in the thymic medulla and secondary lymphoid tissue; and (4) blood dendritic cells and lymph dendritic cells (veiled cells). Although dendritic cells in each of these compartments are all CD45+ leukocytes that arise from the bone marrow, they may exhibit differences that relate to maturation state and microenvironment. Dendritic cells are specialized antigen-presenting cells for T lymphocytes: they process and present antigens efficiently in situ, and stimulate responses from naive and memory T cells in the paracortical area of secondary lymphoid organs. Recent evidence also demonstrates their role in induction of tolerance. By contrast, the primary and secondary B-cell follicles contain follicular dendritic cells that trap and retain intact antigen as immune complexes for long periods of time. The origin of follicular dendritic cells is not clear, but most investigators believe that these cells are not leukocytes.

Table of contents (49 chapters)

  • Characterization of Human CD34+ Derived Dendritic/Langerhans Cells (D-Lc)

    Caux, C. (et al.)

    Pages 1-5

  • Stem Cell Factor Enhances Dendritic Cell Development

    Santiago-Schwarz, Frances (et al.)

    Pages 7-11

  • Synergistic Interaction between c-kit Ligand (SCF), GM-CSF and TNF Promotes Optimal Dendritic Langerhans Cell Proliferation from Primitive Progenitors in Human Bone Marrow

    Saraya, Khaled (et al.)

    Pages 13-16

  • Progenitor Recruitment and in Vitro Expansion of Immunostimulatory Dendritic Cells from Human CD34+ Bone Marrow Cells by c-kit-Ligand, GM-CSF, and TNFα

    Szabolcs, Paul (et al.)

    Pages 17-20

  • Thymic Dendritic Cells: Surface Phenotype, Developmental Origin and Function

    Shortman, Ken (et al.)

    Pages 21-29

Buy this book

eBook $59.99
price for USA in USD (gross)
  • ISBN 978-1-4615-1971-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $79.99
price for USA in USD
  • ISBN 978-1-4613-5811-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Dendritic Cells in Fundamental and Clinical Immunology
Book Subtitle
Volume 2
Editors
  • Jacques Banchereau
  • Daniel Schmitt
Series Title
Advances in Experimental Medicine and Biology
Series Volume
378
Copyright
1995
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-1971-3
DOI
10.1007/978-1-4615-1971-3
Softcover ISBN
978-1-4613-5811-4
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIX, 572
Topics