Developments in Medical Virology

Epstein-Barr Virus and Associated Diseases

Proceedings of the First International Symposium on Epstein-Barr Virus-Associated Malignant Diseases (Loutraki, Greece—September 24–28, 1984)

Editors: Levine, P.H., Ablashi, D.V., Pearson, G.R., Kottaridis, S.D. (Eds.)

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About this book

It has been slightly more than two decades since the Epstein-Barr virus (EBV) was discovered by Prof. M.A. Epstein and his colleagues at the University of Bristol in their search for the causative agent of Burkitt's lymphoma. For several years EBV was a "virus in search of a disease." The first documentation that EBV was pathogenic for humans was in 1969 when Drs. Gertrude and Werner Henle identified it as the causative agent for infectious mononucleosis. Seroepidemiologic and biochemical studies subsequently linked EBV to Burkitt's lymphoma (BL), nasopharyngeal carcinoma (NPC), and more recently to the X-linked lymphoproliferative syndrome. With its widespread pattern of infection and a predilection for producing clinical signs and symptoms in only certain individuals, EBV has provided a model for many other candidate oncogenic viruses, including papilloma viruses, herpes simplex, and HTLV/LAV. In 1975, an international workshop was sponsored by the National Cancer Institute to address the problem of EBV production, thus facilitating basic research on the virus. This proved to be the last international meeting on EBV for almost a decade. In the past, progress in both clinical and basic research on EBV has been presented in two types of international meetings, the international herpesvirus workshops devoted primarily to basic research on both human and animal herpesviruses, and the international symposia on NPC, in which EBV-related studies were interspersed with clinical, epidemiologic and other etiologic aspects of this important human neoplasm.

Table of contents (44 chapters)

  • Association of Epstein-Barr Virus and Lymphoproliferative Diseases in Immune Deficient Persons

    Purtilo, David T., M.D.

    Pages 3-17

  • Relapsing, Recurrent, and Chronic Infectious Mononucleosis in the Normal Host

    Straus, Stephen E., M.D.

    Pages 18-33

  • Immune Assessment of Patients with Chronic Active EBV Infection (CAEBV)

    Jones, J. F. (et al.)

    Pages 34-42

  • Reversal of Common Variable Hypogammaglobulinemia-Associated Suppressor Cell Activity by Specific Carbohydrates

    Tosato, G. (et al.)

    Pages 43-52

  • Unusual Primary Tumors of Brain and Lungs Associated with Epstein-Barr Virus (EBV)

    Joncas, J. (et al.)

    Pages 53-62

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-1-4613-2625-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-1-4612-9641-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Epstein-Barr Virus and Associated Diseases
Book Subtitle
Proceedings of the First International Symposium on Epstein-Barr Virus-Associated Malignant Diseases (Loutraki, Greece—September 24–28, 1984)
Editors
  • P.H. Levine
  • D.V. Ablashi
  • G.R. Pearson
  • S.D. Kottaridis
Series Title
Developments in Medical Virology
Series Volume
1
Copyright
1985
Publisher
Springer US
Copyright Holder
Martinus Nijhoff Publishing, Boston
eBook ISBN
978-1-4613-2625-0
DOI
10.1007/978-1-4613-2625-0
Softcover ISBN
978-1-4612-9641-6
Edition Number
1
Number of Pages
XVI, 694
Topics