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The Bile Acids: Chemistry, Physiology, and Metabolism

Volume 4: Methods and Applications

  • Book
  • © 1988

Overview

Editors:
  1. Kenneth D. R. Setchell

    1. Children’s Hospital Medical Center, Cincinnati, USA

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  2. David Kritchevsky

    1. The Wistar Institute, Philadelphia, USA

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  3. Padmanabhan P. Nair

    1. Lipid Nutrition Laboratory, Beltsville Human Nutrition Research Center, ARS, USDA, Beltsville, USA
      The Johns Hopkins University School of Hygiene and Public Health, Baltimore, USA

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xix
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  2. Techniques for Extraction and Group Separation of Bile Acids

    • J. Sjövall, K. D. R. Setchell
    Pages 1-42

  3. High-Performance Liquid Chromatography

    • Toshio Nambara, Junichi Goto
    Pages 43-64

  4. Nuclear Magnetic Resonance Spectroscopy of Bile Acids

    • Stephen Barnes, David N. Kirk
    Pages 65-136

  5. X-Ray Crystallography

    • S. E. Ealick, C. E. Bugg
    Pages 137-165

  6. Mass Spectrometry of Bile Acids

    • A. M. Lawson, K. D. R. Setchell
    Pages 167-267

  7. Immunological Methods for Serum Bile Acid Analysis

    • A. Roda, E. Roda, D. Festi, C. Colombo
    Pages 269-314

  8. Bioluminescence Assays Using Immobilized Enzymes in Bile Acid Analysis

    • J. Schölmerich, A. Roda, M. DeLuca
    Pages 315-339

  9. Bile Acids in Extrahepatic Tissues

    • Jacqueline Dupont, Pilar A. Garcia, Bernhard Hennig, Nina K. Dodd, Suk Yon Oh, Charles E. Sizer et al.
    Pages 341-372

  10. Tissue-Bound Bile Acids

    • Nabila Turjman, Padmanabhan P. Nair
    Pages 373-378

  11. Serum Bile Acids

    • G. M. Murphy
    Pages 379-403

  12. Urinary Bile Acids

    • Peter Back
    Pages 405-440

  13. Fecal Bile Acids

    • K. D. R. Setchell, J. M. Street, J. Sjövall
    Pages 441-570

  14. Back Matter

    Pages 571-582
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Keywords

About this book

Over a decade has elapsed since the last volume in this series was published. At that time we considered that we had comprehensively covered all aspects relating to bile acid chemistry and physiology. However, major strides have been made in our understanding of the physiology and pathophysiology of bile acids, due largely to the great advances which have taken place in analytical technology. As a result, the need to document these advances was felt acutely, and therefore this volume is devoted to methodologies in bile acid analysis and their applications. This volume includes twelve chapters written by prominent scientists in the field of bile acid research. The initial chapter discusses techniques of extraction and isolation of bile acids from biological fluids. It is followed by descriptions of physical methods of analysis and discussions of the way these techniques have been applied in the field of bile acid research. Of practical value is the inclusion of a comprehensive list of spectra obtained for refer­ ences by nuclear magnetic resonance spectroscopy and mass spectrometry . These chapters are followed by reviews of biological methods of immuno­ assay and bioluminescence. Specific applications of these techniques are then addressed in contributions relating to bile acid analysis of tissue, serum, urine, and feces. With this integrated approach we have attempted to provide a volume which represents a comprehensive review of the analytical field of bile acids, while also serving as a useful reference book for those workers involved in bile acid analysis.

Editors and Affiliations

  • Children’s Hospital Medical Center, Cincinnati, USA

    Kenneth D. R. Setchell

  • The Wistar Institute, Philadelphia, USA

    David Kritchevsky

  • Lipid Nutrition Laboratory, Beltsville Human Nutrition Research Center, ARS, USDA, Beltsville, USA

    Padmanabhan P. Nair

  • The Johns Hopkins University School of Hygiene and Public Health, Baltimore, USA

    Padmanabhan P. Nair

Bibliographic Information

  • Book Title: The Bile Acids: Chemistry, Physiology, and Metabolism

  • Book Subtitle: Volume 4: Methods and Applications

  • Editors: Kenneth D. R. Setchell, David Kritchevsky, Padmanabhan P. Nair

  • DOI: https://doi.org/10.1007/978-1-4613-0901-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1988

  • Softcover ISBN: 978-1-4612-8236-5Published: 02 October 2011

  • eBook ISBN: 978-1-4613-0901-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 604

  • Topics: Gastroenterology, Hepatology, Biochemistry, general

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