40% off Popular Science books & eBooks—Save on general interest titles now!

Advances in Experimental Medicine and Biology

Biochemistry, Molecular Biology, and Physiology of Phospholipase A2 and Its Regulatory Factors

Editors: Mukherjee, Anil B. (Ed.)

Free Preview

Buy this book

eBook $59.99
price for USA in USD
  • ISBN 978-1-4613-0651-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $79.99
price for USA in USD
  • ISBN 978-1-4612-7910-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
About this book

During the past decade there has been a dramatic expansion of our knowledge on phospholipases in general, and phospholipase A2 (PLA2) in particular. Progress in this field has been evident on many fronts, with novel information rapidly accumulating in the literature regarding the chemistry and molecular biology of this enzyme and its role in many important physiological processes. These include cellular signal transduction via the G-protein cycle, and in the generation of many cellular mediators, such as the platelet activating factor (PAF) and the eicosanoids that participate in the initiation and propagation of inflammation, to mention a few. This symposium was organized to obtain an overview of current investigations on this enzyme from the standpoint of its chemistry, molecular biology and physiology. Another important focus of this symposium concerns the regulation of PLA2, including endogenous and synthetic inhibitors and activators of this enzyme. To review these important areas in PLA2 research we invited scientists who made significant contributions in this field. The papers in this volume are organized to emphasize the recent advances in several areas of investigation, including: (I) the structure and mechanism of action of PLA2, (2) mechanism of activation of PLA2, (3) molecular biology, physiology and endogenous inhibitors of this enzyme and finally, (4) clinical investigations emphasizing the pathophysiological role of this enzyme in human diseases. The first article in this volume is by Dr.

Table of contents (17 chapters)

Table of contents (17 chapters)
  • Phospholipases, Enzymes That Share a Substrate Class

    Pages 1-22

    Waite, Moseley

  • Comparative Anatomy of Phospholipase A2 Structures

    Pages 23-36

    Ward, K. B. (et al.)

  • A Novel Bifunctional Mechanism of Surface Recognition by Phospholipase A2

    Pages 37-47

    Heinrikson, Robert L. (et al.)

  • Activation, Aggregation, Inhibition and The Mechanism of Phospholipase A2

    Pages 49-64

    Hazlett, Theordore L. (et al.)

  • Probing the Mechanism of Pancreatic Phospholipase A2 with the Aid of Recombinant DNA Techniques

    Pages 65-84

    Kuipers, O. P. (et al.)

Buy this book

eBook $59.99
price for USA in USD
  • ISBN 978-1-4613-0651-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $79.99
price for USA in USD
  • ISBN 978-1-4612-7910-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Biochemistry, Molecular Biology, and Physiology of Phospholipase A2 and Its Regulatory Factors
Editors
  • Anil B. Mukherjee
Series Title
Advances in Experimental Medicine and Biology
Series Volume
279
Copyright
1990
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4613-0651-1
DOI
10.1007/978-1-4613-0651-1
Softcover ISBN
978-1-4612-7910-5
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VIII, 264
Number of Illustrations
17 b/w illustrations, 1 illustrations in colour
Topics