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Progress in Vaccinology

Anti-Idiotypic Vaccines

Editors: Cazenave, Pierre-Andre (Ed.)

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About this book

Vaccines have historically been considered to be the most cost-effective method for preventing communicable diseases. It was a vaccine~hat enabled global eradication of the dreaded disease smallpox. Mass immunization of children forms the anchor of the strategy of the World Health Organization (WHO) to attain "health for all" status by the year 2000. Vaccinology is undergoing a dimensional change with the advances that have taken place in immunology and genetic engineering. Vaccines that confer short or inadequate immunity or that have side effects are being replaced by better vaccines. New vaccines are being developed for a variety of maladies. Monoclonal antibodies and T cell clones have been employed to delineate the immunodeterminants on microbes, an approach elegantly complemented by computer graphics and molecular imaging techniques. Possibilities have opened for obtaining hitherto scarce antigens of parasites by the DNA recombinant route. Better appreciation of the idiotypic network has aroused research on anti-idiotypic vaccines. Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the sequences activating suppressor cells are discovered and the rules for presentation of antigens to T and B cells are better worked out. A new breed of vaccines is on the horizon that seeks to control fertility.

Table of contents (10 chapters)

Table of contents (10 chapters)
  • Some Thoughts on the Future of Idiotypic Vaccines

    Pages 1-7

    Brait, M. (et al.)

  • Stimulation of Lymphocytic Clones by Anti-Idiotypic Antibodies: Basis for Development of Idiotypic Vaccines

    Pages 8-21

    Bowen, Richard (et al.)

  • Small Human VH Gene Families Show Remarkably Little Polymorphism

    Pages 22-30

    Williams, Carol (et al.)

  • Anti-Idiotypic Vaccines for Carbohydrate Antigens

    Pages 31-41

    Stein, Kathryn E.

  • Characterization of Idiotypic Reagents as Antigen Surrogates of a Human Tumor-Associated Antigen

    Pages 42-54

    Viale, Giovanna (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-1-4612-2992-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $149.00
price for USA in USD
  • ISBN 978-1-4612-7750-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Anti-Idiotypic Vaccines
Editors
  • Pierre-Andre Cazenave
Series Title
Progress in Vaccinology
Series Volume
3
Copyright
1991
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York Inc.
eBook ISBN
978-1-4612-2992-6
DOI
10.1007/978-1-4612-2992-6
Softcover ISBN
978-1-4612-7750-7
Series ISSN
0941-875X
Edition Number
1
Number of Pages
XII, 139
Topics