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Clinical Medicine and the Nervous System

Treatment of Multiple Sclerosis

Trial Design, Results, and Future Perspectives

Editors: Rudick, Richard A., Goodkin, Donald E. (Eds.)

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About this book

Multiple sclerosis is one of the major current problems in neurol­ ogical practice. It remains incompletely understood, yet is a common cause of chronic disability in developed Western so­ cieties: Patients with the disease have difficulty understanding what has happened to them and become bewildered by the con­ trast between the evidently large body of knowledge concerning the clinical manifestations and course of the disease, and the conflicting views they so often receive from different specialists as to the best current management of their disease. As in so many disorders for which treatment is only partially effective, at best, "alternative" therapies abound. Dr. Rudick and Dr. Goodkin have extensive experience in the day-to-day management of multiple sclerosis at the Mellen Center for Multiple Sclerosis Treatment and Research, attached to the Cleveland Clinic. In this book they have assembled a group of experts from several countries and have provided a comprehensive review of the results of different treatments of the disease. Each treatment is considered in the light of its proposed scientific basis or mode of action, and in relation to ethical and trial design issues. This information deserves to be made widely available. As the treatment of multiple sclerosis enters a new era as a result of the new understanding of the cellular mechanisms of demyelination and the molecular biology of the immune response, this information about current treatments assumes additional importance. The book is of interest to all physicians concerned with the management of patients with the disease.

Table of contents (15 chapters)

Table of contents (15 chapters)
  • Experimental Therapies for Multiple Sclerosis: Historical Perspective

    Pages 1-15

    Ellison, George W.

  • The Natural History of Multiple Sclerosis

    Pages 17-45

    Goodkin, Donald E.

  • Assessing the Outcome of Experimental Therapies in Multiple Sclerosis Patients

    Pages 47-90

    Paty, Donald (et al.)

  • Design and Statistical Issues Related to Testing Experimental Therapy in Multiple Sclerosis

    Pages 91-122

    Weiss, William (et al.)

  • Pathogenesis of Multiple Sclerosis: Relationship to Therapeutic Strategies

    Pages 123-133

    Ransohoff, Richard M.

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-1-4471-3184-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-1-4471-3186-1
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Treatment of Multiple Sclerosis
Book Subtitle
Trial Design, Results, and Future Perspectives
Editors
  • Richard A. Rudick
  • Donald E. Goodkin
Series Title
Clinical Medicine and the Nervous System
Copyright
1992
Publisher
Springer-Verlag London
Copyright Holder
Springer-Verlag London Limited
eBook ISBN
978-1-4471-3184-7
DOI
10.1007/978-1-4471-3184-7
Softcover ISBN
978-1-4471-3186-1
Series ISSN
1431-147X
Edition Number
1
Number of Pages
XVIII, 313
Topics

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