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Diseases of the Human Carotid Body

Authors: Heath, Donald, Smith, Paul

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About this book

Ever since its discovery in 1742 the carotid body has remained an organ of mystery. Originally described as a ganglion, it was subsequently regarded as a gland, chromaffin paraganglion and non-chromaffin paraganglion. In 1928 it was shown to be a chemoreceptor with close associations with the function of baroreception in the adjacent carotid sinus and perhaps within its own substance. These discoveries led physiologists to embark on a series of elegant experimental studies on a number of animal species which have, however, so far failed to identify the transducer for detection of changes in tension of arterial blood gases or the mechanism of chemorĀ­ eception. Pathologists on the other hand have largely ignored the carotid body, restricting their interest to its tumour, the chemodectoma. A remarkable disparity in knowledge of the organ has resulted, with most information being available on the physiology of chemoreceptor tissue in laboratory animals. In contrast, there has been sparse interest and awareness of the pathology in man of this nodule of tissue lying in the carotid bifurcation whose functional activity is suggested by the high blood flow it receives, and its rich content of biogenic amines and a wide variety of peptides. This book is an attempt to redress this unsatisfactory situation. During the last few years our understanding of the detailed histology and ultrastructure of the human carotid body has improved.

Table of contents (21 chapters)

Table of contents (21 chapters)
  • The Nature of the Carotid Body

    Pages 1-6

    Heath, Donald, DSc, MD, PhD, FRCP, FRCPEd, FRCPath (et al.)

  • Size, Weight and Anatomical Variation

    Pages 7-13

    Heath, Donald, DSc, MD, PhD, FRCP, FRCPEd, FRCPath (et al.)

  • Normal Histology

    Pages 15-24

    Heath, Donald, DSc, MD, PhD, FRCP, FRCPEd, FRCPath (et al.)

  • Histological Changes Associated with Ageing of the Adult Carotid Body

    Pages 25-29

    Heath, Donald, DSc, MD, PhD, FRCP, FRCPEd, FRCPath (et al.)

  • The Carotid Bodies in Fetuses, Neonates and Infants

    Pages 31-41

    Heath, Donald, DSc, MD, PhD, FRCP, FRCPEd, FRCPath (et al.)

Buy this book

eBook $84.99
price for USA in USD
  • ISBN 978-1-4471-1874-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-1-4471-1876-3
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually ready to be dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Diseases of the Human Carotid Body
Authors
Copyright
1992
Publisher
Springer-Verlag London
Copyright Holder
Springer-Verlag London Limited
eBook ISBN
978-1-4471-1874-9
DOI
10.1007/978-1-4471-1874-9
Softcover ISBN
978-1-4471-1876-3
Edition Number
1
Number of Pages
XII, 205
Number of Illustrations
99 b/w illustrations
Topics

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