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Platelet-Vessel Wall Interactions

  • Book
  • © 1988

Overview

Editors:
  1. R. Michael Pittilo

    1. Bland-Sutton Institute, Department of Histopathology, The Middlesex Hospital, London, UK
      Department of Analytical and Biological Chemistry, Kingston Polytechnic, Kingston-upon-Thames, Surrey, UK

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  2. Samuel J. Machin

    1. Department of Haematology, School of Pathology, The Middlesex Hospital, London, UK

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: The Bloomsbury Series in Clinical Science (BLOOMSBURY)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-xiv
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  2. The Platelet

    • Ian J. Mackie, Christopher R. Neal
    Pages 1-32

  3. Endothelium and the Vessel Wall

    • R. Michael Pittilo
    Pages 33-59

  4. The use of Cultured Endothelial Cells in the Study of Platelet-Vessel Wall Interactions

    • Helen A. Bull
    Pages 61-86

  5. Smoking and Platelet-Vessel Wall Interactions

    • R. Michael Pittilo
    Pages 87-101

  6. Mesothelium as a Non-thrombogenic Surface

    • Carol M. Blow
    Pages 103-119

  7. Platelet-Endothelial Interactions in Renal Injury

    • Guy H. Neild, Michael P. Gordge
    Pages 121-153

  8. Haemolytic Uraemic Syndrome and Thrombotic Thrombocytopenic Purpura: A Review

    • Guy H. Neild
    Pages 155-165

  9. Newer Pharmacological Agents

    • Anne Yardumian, Samuel J. Machin
    Pages 167-191

  10. Back Matter

    Pages 193-198
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Keywords

About this book

The publication of Platelet-Vessel Wall Interactions, the second monograph in the Bloomsbury Series in Clinical Science, is particu­ larly welcome as its appearance signifies the further development of the Series and its potential for the future. The theme of this monograph is the pathophysiology of atherosclerosis, a topic that symbolises the aim of the Series, namely to highlight the important interfaces between basic medical science and clinical practice. Our congratulations to the Editors and contributors. London, December 1987 lack Tinker Preface In the Western world, atherosclerosis causes more illness and death than any other disease. Despite its devastating effects, the pathogenesis of the disease remains a matter for hypothesis and con­ jecture. This monograph owes its conception to a programme of work directed towards understanding the basic pathophysiology of atherosclerosis. The circulatory system is lined by vascular endothelium which has a central role in maintaining the integrity of the vessel wall and prevent­ ing thrombosis. The natural equilibrium existing between normal en­ dothelium which supports blood flow, and platelets which serve to re­ pair damaged endothelium, is explored in the first two chapters. Atherosclerosis developing as a response to endothelial injury is one hypothesis which has stimulated widespread interest, and re­ search has largely been directed towards finding the injurious agent.

Editors and Affiliations

  • Bland-Sutton Institute, Department of Histopathology, The Middlesex Hospital, London, UK

    R. Michael Pittilo

  • Department of Analytical and Biological Chemistry, Kingston Polytechnic, Kingston-upon-Thames, Surrey, UK

    R. Michael Pittilo

  • Department of Haematology, School of Pathology, The Middlesex Hospital, London, UK

    Samuel J. Machin

Bibliographic Information

  • Book Title: Platelet-Vessel Wall Interactions

  • Editors: R. Michael Pittilo, Samuel J. Machin

  • Series Title: The Bloomsbury Series in Clinical Science

  • DOI: https://doi.org/10.1007/978-1-4471-1455-0

  • Publisher: Springer London

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1988

  • Softcover ISBN: 978-1-4471-1457-4Published: 15 November 2011

  • eBook ISBN: 978-1-4471-1455-0Published: 06 December 2012

  • Series ISSN: 0939-2491

  • Edition Number: 1

  • Number of Pages: XIV, 198

  • Topics: Hematology, Cardiology

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