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Advances in Experimental Medicine and Biology

Epigenetic Contributions in Autoimmune Disease

Editors: Ballestar, Esteban (Ed.)

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  • Overview of some of the key concepts in epigenetics, chromatin and the interaction with transcription factors
  • Shows the specific influence of environmental factors to influence or trigger the autoimmune response
  • Discusses the possibilities of using epigenetics-based therapies in the context of autoimmune diseases
  • Presents the application of novel methods to characterize the epigenetic profile
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About this book

This volume focuses on the relevance of epigenetic mechanisms in autoimmune disease. It provides new directions for future research in autoimmune disease.

About the authors

ESTEBAN BALESTAR is head of the Chromatin and Disease Group at the Cancer Epigenetics and Biology Programme (PEBC) of the Bellvitge Biomedical Research Institute (IDIBELL ) in Barcelona, Spain. Ballestar obtained his PhD degree from the University of Valencia under the supervision of Prof. Luis Franco, specialising in chromatin and histone modifications (1997). He then worked as a Postdoctoral Fellow at the National Institutes of Health, (Bethesda, MD, USA) in the laboratory of Dr. Alan Wolffe where he investigated associations between elements of the chromatin machinery and methylated DNA. From 2001 to 2008, Esteban Ballestar has worked at the CNIO Cancer Epigenetics Laboratory, in association with Dr. Manel Esteller, where his principal area of research has been the study of the implication of chromatin factors in epigenetic alterations in human cancer. His current research is devoted to the establishment of different mechanisms of epigenetic deregulation in the context of the hematopoietic system in both autoimmune diseases and hematological malignancies.

Table of contents (12 chapters)

Table of contents (12 chapters)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-1-4419-8216-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-1-4419-8215-5
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Online orders shipping within 2-3 days.
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Bibliographic Information

Bibliographic Information
Book Title
Epigenetic Contributions in Autoimmune Disease
Editors
  • Esteban Ballestar
Series Title
Advances in Experimental Medicine and Biology
Series Volume
711
Copyright
2011
Publisher
Springer US
Copyright Holder
Landes Bioscience and Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-8216-2
DOI
10.1007/978-1-4419-8216-2
Hardcover ISBN
978-1-4419-8215-5
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XVI, 182
Topics

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