Signaling Pathways in Squamous Cancer

Editors: Glick, Adam B., Waes, Carter Van (Eds.)

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  • Brings together reviews from experts who study mechanisms and signaling pathways that regulate development of squamous cancer in a variety of tissue sites, in both human and experimental mouse models
  • There is focus on how these specific signaling pathways can be utilized as targets for anti-cancer therapy
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eBook $219.00
price for USA in USD (gross)
  • ISBN 978-1-4419-7203-3
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  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-1-4419-7202-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.99
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  • ISBN 978-1-4899-8234-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Squamous epithelia form the essential lining surface of tissues in contact with the environment, including the skin, and mucosa of the oral cavity, pharynx, larynx, esophagus, respiratory and genital tracts, and several other specialized tissues. These tissues are at highest risk for exposure to environmental carcinogens such as UV light, tobacco smoke, and infectious agents. Consequently, squamous cell carcinomas that form in these tissues are among the most common human solid tumors, and have high morbidity and mortality. The signaling pathways that regulate epithelial homeostasis and the alterations in these pathways that arise during cancer development share certain features among these different tissue sites. This book brings together timely reviews from experts in the field on mechanisms and signaling pathways such as EGFR, TGF1, NFB, PPARs and mTOR/AKT that regulate development of squamous cancer in both human and experimental mouse models, with a focus on how these specific signaling pathways can be utilized as targets for anti-cancer therapy. This comprehensive monograph will be important for researchers wishing to enter the field, for medical students, and for established basic and clinical investigators who would gain from an overview of the field.

Table of contents (20 chapters)

Table of contents (20 chapters)
  • Cell Adhesion Molecules in Carcinoma Invasion and Metastasis

    Ziober, Barry L. (et al.)

    Pages 1-19

  • Roles of Integrins in the Development and Progression of Squamous Cell Carcinomas

    Lamar, John (et al.)

    Pages 21-52

  • Alterations of Transforming Growth Factor-β Signaling in Squamous Cell Carcinomas

    Xie, Wen (et al.)

    Pages 53-89

  • Aberrant Activation of HGF/c-MET Signaling and Targeted Therapy in Squamous Cancer

    Chen, Zhong

    Pages 91-111

  • The Epidermal Growth Factor Receptor in Normal and Neoplastic Epithelia

    Repertinger, Susan K. (et al.)

    Pages 113-129

Buy this book

eBook $219.00
price for USA in USD (gross)
  • ISBN 978-1-4419-7203-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-1-4419-7202-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.99
price for USA in USD
  • ISBN 978-1-4899-8234-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Signaling Pathways in Squamous Cancer
Editors
  • Adam B. Glick
  • Carter Van Waes
Copyright
2011
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-7203-3
DOI
10.1007/978-1-4419-7203-3
Hardcover ISBN
978-1-4419-7202-6
Softcover ISBN
978-1-4899-8234-6
Edition Number
1
Number of Pages
XX, 462
Topics