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  • © 2010

Post‑Transcriptional Regulation by STAR Proteins

Control of RNA Metabolism in Development and Disease

  • Reviews the available information on the structure of the RNA binding STAR domain and provides insights into how these proteins discriminate between different RNA targets
  • Overviews of the post-translational modifications of STAR proteins and their effects on biological functions
  • Reviews what is known about STAR proteins and human disease including osteoporosis, schizophrenia, cancer, infertility and ataxia

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 693)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xviii
  2. Star Trek

    • Karen Artzt, Jiang I. Wu
    Pages 1-24
  3. The Star Family Member

    • Yue Feng, Andrew Bankston
    Pages 25-36
  4. The Role of Quaking in Mammalian Embryonic Development

    • Monica J. Justice, Karen K. Hirschi
    Pages 82-92
  5. Drosophila STAR Proteins

    • Talila Volk
    Pages 93-105
  6. The Branchpoint Binding Protein

    • Brian C. Rymond
    Pages 123-141
  7. Reaching for the STARs

    • Stéphane Richard
    Pages 142-157
  8. Back Matter

    Pages 159-162

Editors and Affiliations

  • Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

    Talila Volk

  • Department of Molecular Genetics and Microbiology, Institute of Cell and Molecular Biology, University of Texas at Austin, Austin, USA

    Karen Artzt

About the editors

Talila Volk is an associate professor in the field of Developmental Biology and the incumbent of the Sir Ernest B. Chain Professional Chair. Her major research interest is in tissue morphogenesis and organogenesis during embryonic development. She has been studying the function and activity of the STAR family member Held Out Wing (HOW) in the fruit fly Drosophila since 1999. She served as the chair for the Society of Developmental Biology in Israel (ISDB). Dr. Volk has gained her BSc from Tel‑Aviv University, and her MSc and PhD degrees from the Weizmann Institute of Science, Rehovot, Israel. Karen Artzt is an Ashbel Smith Professor Emeritus at the University of Texas at Austin where she directed a research laboratory for 20 years. There she was a member of the Section of Molecular Genetics and Microbiology. Prior to that she was an associate Member of the Memorial Sloan Kettering Cancer Center in New York. Her main research interests include developmental genetics with an emphasis on cancer biology. In collaboration with Tom Ebersole she identified and cloned the mouse gene quaking that was one of the founding members of the STAR family. Dr. Artzt received her academic degrees from Cornell university; a BA from the Ithaca campus and a PhD from the Medical College School of Graduate Sciences in New York City. In 1972 she spent a year as a postdoctoral fellow at the Pasteur Institute in Paris under the direction of the Nobel Prize winner, Francois Jacob.

Bibliographic Information

  • Book Title: Post‑Transcriptional Regulation by STAR Proteins

  • Book Subtitle: Control of RNA Metabolism in Development and Disease

  • Editors: Talila Volk, Karen Artzt

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4419-7005-3

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2010

  • Hardcover ISBN: 978-1-4419-7004-6Published: 01 September 2010

  • Softcover ISBN: 978-1-4899-7805-9Published: 23 August 2016

  • eBook ISBN: 978-1-4419-7005-3Published: 11 January 2011

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVIII, 162

  • Topics: Pharmacology/Toxicology, Neurosciences

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access