Advances in Experimental Medicine and Biology

Insect Nicotinic Acetylcholine Receptors

Editors: Thany, Steeve Hervé (Ed.)

  • Illustrates the finding that the insect central nervous system is extremely rich in acetylcholine receptors which have a predominantly nicotinic pharmacology
  • Demonstrates that several amino acids that account for ligand binding domain are conserved in the insect nicotinic receptor subunit
  • Explores the involvement of insect nicotinic receptors in learning and memory processes, using the honeybee as insect model
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About this book

The aim of this book is to summarize our understanding on the insect nicotinic acetylcholine receptors. This area of research received great impetus from the identification of the first subunit sequences to be used as neonicotinoid insecticide target sites. Although a book of this nature can provide the details only of commonly published results, it is hoped that it may provide a useful guide to the newcomer to the field as well as to point out some of the future challenges. For example, we need to determine the precise subunit nomenclature of insect nicotinic receptors. This nomenclature varies amongst species and this led to some of the early confusion that persists. We need to be precise in identifying the subunit composition of native insect nicotinic receptor subtypes, their functional properties and physiological roles.

About the authors

Steeve Hervé Thany is an assistant Professor for Neurobiology and Neurophysiology at the University of Angers, France. Its research interests are in the areas of molecular biology, electrophysiology, pharmacology and behavioral processes involving insect nicotinic acetylcholine receptors. Recent research focused on the effects of neonicotinoid insecticides on nicotinic receptors and the intracellular mechanisms regulating their function. He is a member of numerous national and international scientific organisations, including the French Society for Neuroscience (SN) and the Federation of European Neuroscience Societies (FENS).

Table of contents (9 chapters)

  • Identification of Cholinergic Synaptic Transmission in the Insect Nervous System

    Thany, Steeve Hervé (et al.)

    Pages 1-10

  • The Evolution of Pentameric Ligand-Gated Ion Channels

    Dent, Joseph A.

    Pages 11-23

  • Diversity of Insect Nicotinic Acetylcholine Receptor Subunits

    Jones, Andrew K. (et al.)

    Pages 25-43

  • Identification of Critical Elements Determining Toxins and Insecticide Affinity, Ligand Binding Domains and Channel Properties

    Tricoire-Leignel, Hélène (et al.)

    Pages 45-52

  • Electrophysiological Studies and Pharmacological Properties of Insect Native Nicotinic Acetylcholine Receptors

    Thany, Steeve Hervé

    Pages 53-63

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-1-4419-6445-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-4419-6444-1
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
Softcover $159.99
price for USA in USD
  • ISBN 978-1-4939-5153-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Insect Nicotinic Acetylcholine Receptors
Editors
  • Steeve Hervé Thany
Series Title
Advances in Experimental Medicine and Biology
Series Volume
683
Copyright
2010
Publisher
Springer-Verlag New York
Copyright Holder
Landes Bioscience and Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-6445-8
DOI
10.1007/978-1-4419-6445-8
Hardcover ISBN
978-1-4419-6444-1
Softcover ISBN
978-1-4939-5153-6
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIX, 118
Topics