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Advances in Experimental Medicine and Biology

Therapeutic Applications of Cell Microencapsulation

Editors: Pedraz, Jose Luis, Orive, Gorka (Eds.)

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  • - Provides a detailed and up-to-date account of the state-of-the-art in the field of cell encapsulation

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About this book

The advancement of science is ever more contingent upon the interaction of experts vast amount of scientific information being gathered every day that exceeds the ability of any one scientist to acquire. As an illustration of the frantic pace of scientific disc- more acute in the case of scientific fields at the interface of different and seemingly distant areas of study. Amidst these, the field of cell encapsulation brings together an array of diverse disciplines such as molecular biology and biopolymers, gene therapy and inorganic membranes, stem cell biology and physicochemistry, immunology and nanotechnology. Clearly, such range of topics is too broad for any individual scientist the state-of-the-art in the field of cell encapsulation. At the core of this technology, there is an interaction of physicochemical and biological elements forming three distinct layers of complexity. First, the chemistry of the biopolymer dictates the degree of protein adsorption, vascularization, tox- ity and biocompatibility of the microcapsules. Advances in biopolymer science are providing solutions to overcome existing challenges and to improve microcapsules as delivery vehicles. Second, the choice of cells, and more precisely the plethora of in determining the immune response elicited by the host to implanted microcapsules.

About the authors

José Luis Pedraz has a PhD in Pharmacy from the University of Salamanca, Spain. He is professor of Pharmacy and Pharmaceutical Technology at the Faculty of Pharmacy in the Basque Country University. He is cofounder and director of the Pharmaceutical Development Unit of the Basque Country. His interest is focused in the development and evaluation of pharmaceutical dosage forms (microcapsules, micro- and nanoparticles) for the administration of gene, proteins, peptides, vaccines and cells. He has published over 200 scientific articles and edited several book chapters focused on cell microencapsulation.

Gorka Orive has a PhD in Pharmacy and is currently assistant professor of Pharmacy and Pharmaceutical Technology at the University of the Basque Country in Vitoria, Spain. He is director of research publications and scientific coordinator of the field of oral implantology for Biotechnology Institute (BTI, Vitoria, Spain). His interests include polymer-based cell therapy for long-term and controlled protein and growth factor delivery to different tissues including brain. He is also interested in the potential use of autologous platelets growth factors and fibrin scaffold for regenerative medicine. He has published more than 100 articles in national and international journals including Nature Medicine, Nature Reviews Neurosciences, Molecular Therapy, Biomaterials, Trends in Pharmacological Sciences among others and several book chapters focused on cell microencapsulation for therapeutic purposes and the use of plasma rich in growth factors in medicine.

Table of contents (12 chapters)

Table of contents (12 chapters)

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-1-4419-5786-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-1-4419-5785-6
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Online orders shipping within 2-3 days.
Softcover $169.99
price for USA in USD
  • ISBN 978-1-4614-2549-6
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Therapeutic Applications of Cell Microencapsulation
Editors
  • Jose Luis Pedraz
  • Gorka Orive
Series Title
Advances in Experimental Medicine and Biology
Series Volume
670
Copyright
2010
Publisher
Springer-Verlag New York
Copyright Holder
Landes Bioscience and Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-5786-3
DOI
10.1007/978-1-4419-5786-3
Hardcover ISBN
978-1-4419-5785-6
Softcover ISBN
978-1-4614-2549-6
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XXII, 125
Number of Illustrations
27 b/w illustrations, 5 illustrations in colour
Topics

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