Computer Simulation and Data Analysis in Molecular Biology and Biophysics
An Introduction Using R
Authors: Bloomfield, Victor
Free Preview- Covers many of the major quantitative topics in modern molecular and cell biology and biophysics
- Presents both standard and cutting-edge topics such as regulation of metabolism and development
- Treats both computer simulation and statistics
- Takes a computational approach that most students find more appealing than analytical mathematics
- Uses the powerful, open-source, cross-platform computer language R
Buy this book
- About this book
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This book provides an introduction, suitable for advanced undergraduates and beginning graduate students, to two important aspects of molecular biology and biophysics: computer simulation and data analysis. It introduces tools to enable readers to learn and use fundamental methods for constructing quantitative models of biological mechanisms, both deterministic and with some elements of randomness, including complex reaction equilibria and kinetics, population models, and regulation of metabolism and development; to understand how concepts of probability can help in explaining important features of DNA sequences; and to apply a useful set of statistical methods to analysis of experimental data from spectroscopic, genomic, and proteomic sources.
These quantitative tools are implemented using the free, open source software program R. R provides an excellent environment for general numerical and statistical computing and graphics, with capabilities similar to Matlab®. Since R is increasingly used in bioinformatics applications such as the BioConductor project, it can serve students as their basic quantitative, statistical, and graphics tool as they develop their careers
- Reviews
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From the reviews: “This book targets biochemistry and molecular biophysics students who have prior knowledge of a few subjects, including mathematics, statistics, and modeling, and possess very basic programming skills. Examples and illustrations are ample throughout the text, and the writing style is plain and efficient. … this book mostly appropriate for students or researchers who have prior exposure to the related subjects. Summing Up: Recommended. Upper-division undergraduates through researchers/faculty.” (D. Papamichail, Choice, Vol. 47 (5), January, 2010)
- Table of contents (14 chapters)
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Calculating with R
Pages 3-22
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Plotting with R
Pages 23-47
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Functions and Programming
Pages 49-67
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Data and Packages
Pages 69-82
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Equilibrium and Steady State Calculations
Pages 85-112
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Table of contents (14 chapters)
- Download Preface 1 PDF (77.9 KB)
- Download Sample pages 1 PDF (2.4 MB)
- Download Table of contents PDF (99.5 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Computer Simulation and Data Analysis in Molecular Biology and Biophysics
- Book Subtitle
- An Introduction Using R
- Authors
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- Victor Bloomfield
- Series Title
- Biological and Medical Physics, Biomedical Engineering
- Copyright
- 2009
- Publisher
- Springer-Verlag New York
- Copyright Holder
- Springer-Verlag New York
- eBook ISBN
- 978-1-4419-0083-8
- DOI
- 10.1007/978-1-4419-0083-8
- Hardcover ISBN
- 978-1-4419-0084-5
- Softcover ISBN
- 978-1-4899-8520-0
- Series ISSN
- 1618-7210
- Edition Number
- 1
- Number of Pages
- XVI, 321
- Topics
