Cancer Microenvironment and Therapeutic Implications
Tumor Pathophysiology Mechanisms and Therapeutic Strategies
Editors: Baronzio, Gianfranco, Fiorentini, Giammaria, Cogle, Christopher R. (Eds.)
Free Preview- Offers a bird’s-eye view of cancer biology
- Presents a critical appraisal of cancer’s context in addition to its substance
- Written by a team of physician-scientists merging experiences at the lab bench with the fight in the cancer clinic
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- About this book
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In the post-genomic era, cancer is a genetic disease. However, cancer genotype does not always equal cancer phenotype. Cancers with the same genetic abnormalities don’t always behave the same. Understanding and eradicating cancers will require an appreciation for cancer’s ecology.
This book is the first to comprehensively explore and critically appraise cancer microenvironments and host interactions with an eye towards exploiting our understanding for new treatments. The team of contributors share amongst them impressive experiences at the laboratory bench and in the clinic. These physician-scientists have dedicated themselves to the tension between the urgency for cures and the technical challenges of discovery.
The target audience includes clinical oncologists, clinical hematologists, research oncologists, research hematologists, immunologists, stem cell researchers, oncology and hematology fellows (trainees), oncology educators (graduate and undergraduate levels), and course book for graduate students and undergraduate students.
- Table of contents (12 chapters)
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Inflammation and Carcinogenesis: A Change in the Metabolic Process
Pages 3-18
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Tumor Microenvironment: Aspects of Stromal-Parenchymal Interaction
Pages 19-38
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Significance of Tumor Microenvironment on the Genesis of: Interstitial Fluid, Angiogenesis, Haemostatic/Haemorheologic Abnormalities. Pathogenesis and Therapeutic Aspects
Pages 39-61
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Cancer, Stem Cells and the Neoplastic Niche
Pages 63-78
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Barriers to Drug Delivery in Cancer: Clinical Implications
Pages 81-104
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Table of contents (12 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Cancer Microenvironment and Therapeutic Implications
- Book Subtitle
- Tumor Pathophysiology Mechanisms and Therapeutic Strategies
- Editors
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- Gianfranco Baronzio
- Giammaria Fiorentini
- Christopher R. Cogle
- Copyright
- 2009
- Publisher
- Springer Netherlands
- Copyright Holder
- Springer Science+Business Media B.V.
- eBook ISBN
- 978-1-4020-9576-4
- DOI
- 10.1007/978-1-4020-9576-4
- Hardcover ISBN
- 978-1-4020-9575-7
- Softcover ISBN
- 978-90-481-8160-5
- Edition Number
- 1
- Number of Pages
- XVI, 242
- Topics
