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Learning from Nature How to Design New Implantable Biomaterials: From Biomineralization Fundamentals to Biomimetic Materials and Processing Routes

Proceedings of the NATO Advanced Study Institute, held in Alvor, Algarve, Portugal, 13-24 October 2003

  • Conference proceedings
  • © 2005

Overview

Editors:
  1. R. L. Reis

    1. Department of Polymer Engineering, University of Minho, Braga, Portugal

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  2. S. Weiner

    1. Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: NATO Science Series II: Mathematics, Physics and Chemistry (NAII, volume 171)

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Table of contents (13 papers)

  1. Front Matter

    Pages i-xv
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  2. Structure and Mechanical Functions in Biological Materials

    1. Structure-Mechanical Function Relations in Bones and Teeth

      • S. Weiner, P. Zaslansky
      Pages 3-13

    2. Hierarchical Structure and Mechanical Adaptation of Biological Materials

      • Peter Fratzl
      Pages 15-34

  3. Bioceramics, Bioactive Materials and Surface Analysis

    1. Calcium Phosphate Biomaterials: An Overview

      • Huipin Yuan, Klaas de Groot
      Pages 37-57

    2. Nanostructural Control of Implantable Xerogels for the Controlled Release of Biomolecules

      • Shula Radin, Paul Ducheyne
      Pages 59-74

    3. Surface Analysis of Biomaterials and Biomineralization

      • Buddy D. Ratner
      Pages 75-85

  4. Biomimetics and Biomimetic Coatings

    1. Biomimetics and Bioceramics

      • B. Ben-Nissan
      Pages 89-103

    2. New Biomimetic Coating Technologies and Incorporation of Bioactive Agents and Proteins

      • P. Habibovic, F. Barrère, K. de Groot
      Pages 105-121

    3. Learning from Nature How to Design Biomimetic Calcium-Phosphate Coatings

      • I. B. Leonor, H. S. Azevedo, I. Pashkuleva, A. L. Oliveira, C. M. Alves, R. L. Reis
      Pages 123-150

    4. Learning from Marine Creatures How to Design Micro-Lenses

      • J. Aizenberg, G. Hendler
      Pages 151-166

  5. Tissue Engineering of Mineralized Tissues

    1. Inkjet Printing for Biomimetic and Biomedical Materials

      • Paul Calvert, Yuka Yoshioka, Ghassan Jabbour
      Pages 169-180

    2. Stem Cells and Bioactive Materials

      • Robert C. Bielby, Julia M. Polak
      Pages 181-198

    3. Embryonic Stem Cells for the Engineering and Regeneration of Mineralized Tissues

      • Lee D.K. Buttery, Julia M. Polak
      Pages 199-204

    4. Tissue Engineering of Mineralized Tissues: The Essential Elements

      • A. J. Salgado, M. E. Gomes, R. L. Reis
      Pages 205-222

  6. Back Matter

    Pages 223-233
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Keywords

About this book

The development of materials for any replacement or regeneration application should be based on the thorough understanding of the structure to be substituted. This is true in many fields, but particularly exigent in substitution and regeneration medicine. The demands upon the material properties largely depend on the site of application and the function it has to restore. Ideally, a replacement material should mimic the living tissue from a mechanical, chemical, biological and functional point of view. Of course this is much easier to write down than to implement in clinical practice. Mineralized tissues such as bones, tooth and shells have attracted, in the last few years, considerable interest as natural anisotropic composite structures with adequate mechanical properties. In fact, Nature is and will continue to be the best materials scientist ever. Who better than nature can design complex structures and control the intricate phenomena (processing routes) that lead to the final shape and structure (from the macro to the nano level) of living creatures? Who can combine biological and physico-chemical mechanisms in such a way that can build ideal structure-properties relationships? Who, else than Nature, can really design smart structural components that respond in-situ to exterior stimulus, being able of adapting constantly their microstructure and correspondent properties? In the described philosophy line, mineralized tissues and biomineralization processes are ideal examples to learn-from for the materials scientist of the future.

Editors and Affiliations

  • Department of Polymer Engineering, University of Minho, Braga, Portugal

    R. L. Reis

  • Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel

    S. Weiner

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