The Brain Without Oxygen

Causes of Failure-Physiological and Molecular Mechanisms for Survival

Authors: Lutz, P.L., Nilsson, G.E., Prentice, H.M.

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About this book

It is well known and researched, that deprivation of oxygen to the brain can quickly result in irreversible damage and death. What is less well known, is that some vertebrate species are exceptionally tolerant of brain hypoxia. The Brain Without Oxygen: Causes of failure - Physiological and molecular mechanisms for survival, Third edition, discusses the mechanisms of brain hypoxia tolerance in these exceptional vertebrates, which include diving marine mammals, high altitude dwellers and the hibernating mammal. Special attention is given to the extraordinary adaptations that allow a few turtle and fish species to tolerate months of brain anoxia.

This third, fully updated edition addresses the potential of these animal models as targets for human clinical intervention. Perhaps the most interesting of these, are those involved in the suppression of metabolic activities to new set points well below their normoxic minima or maintenance levels. This volume will be valuable reading for researchers in physiology, medicine and general biological sciences, and of great importance to pharmaceutical companies researching novel models for stroke and brain ischemia.

Table of contents (10 chapters)

Table of contents (10 chapters)

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-0-306-48197-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-1-4020-1165-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.99
price for USA in USD
  • ISBN 978-90-481-6237-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Brain Without Oxygen
Book Subtitle
Causes of Failure-Physiological and Molecular Mechanisms for Survival
Authors
Copyright
2003
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-0-306-48197-0
DOI
10.1007/0-306-48197-9
Hardcover ISBN
978-1-4020-1165-8
Softcover ISBN
978-90-481-6237-6
Edition Number
3
Number of Pages
VIII, 252
Topics