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Table of contents (13 chapters)
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Front Matter
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Back Matter
About this book
Chapters in this book review the remarkable advances in the field of zinc biology over the last decade. Zinc is essential for life, in particular for growth and development, through its role in hundreds of zinc enzymes and thousands of zinc proteins. Its catalytic, structural, and regulatory functions in these proteins impact metabolism, gene expression, and signal transduction, including neurotransmission. Among the micronutrients, zinc may rank with iron as to its importance for public health.
The topics covered range from single molecules to cells and to whole organisms: the chemistry, design, and application of fluorophores for the determination of cellular zinc; the role of zinc in proliferation, differentiation, and apoptosis of cells; proteins that transport, sense, and distribute zinc and together form a cellular homeostatic system; the coordination chemistry of zinc in metalloproteins; the role of zinc in the brain as a neuromodulator/transmitter; the dependence of the immune system on zinc; zinc homeostasis in the whole human body.
Editors and Affiliations
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Center for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, Boston, USA
W. Maret
Bibliographic Information
Book Title: Zinc Biochemistry, Physiology, and Homeostasis
Book Subtitle: Recent Insights and Current Trends
Editors: W. Maret
DOI: https://doi.org/10.1007/978-94-017-3728-9
Publisher: Springer Dordrecht
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media Dordrecht 2001
Hardcover ISBN: 978-1-4020-0217-5Published: 31 January 2002
Softcover ISBN: 978-90-481-5916-1Published: 07 December 2010
eBook ISBN: 978-94-017-3728-9Published: 11 November 2013
Edition Number: 1
Number of Pages: IV, 232
Additional Information: Reprinted from BIOMETALS, 14:3-4
Topics: Medicinal Chemistry, Biochemistry, general, Inorganic Chemistry, Nutrition