Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 2399)
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Table of contents (18 protocols)
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Front Matter
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Systems Biology of the Genome, Epigenome, and Redox Proteome
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Front Matter
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Systems Biology of Metabolic Networks
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Front Matter
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Systems Biology of Aging and Longevity
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Front Matter
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Systems Biology of Disease
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Front Matter
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Systems Biology of Rhythms, Morphogenesis, and Complex Dynamics
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Front Matter
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Keywords
About this book
This volume addresses the latest state-of-the-art systems biology-oriented approaches that--driven by big data and bioinformatics--are utilized by Computational Systems Biology, an interdisciplinary field that bridges experimental tools with computational tools to tackle complex questions at the frontiers of knowledge in medicine and biotechnology. The chapters in this book are organized into six parts: systems biology of the genome, epigenome, and redox proteome; metabolic networks; aging and longevity; systems biology of diseases; spatiotemporal patterns of rhythms, morphogenesis, and complex dynamics; and genome scale metabolic modeling in biotechnology. In every chapter, readers will find varied methodological approaches applied at different levels, from molecular, cellular, organ to organisms, genome to phenome, and health and disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics; criteria utilized for applying specific methodologies; lists of the necessary materials, reagents, software, databases, algorithms, mathematical models, and dedicated analytical procedures; step-by-step, readily reproducible laboratory, bioinformatics, and computational protocols all delivered in didactic and clear style and abundantly illustrated with express case studies and tutorials; and tips on troubleshooting and advice for achieving reproducibility while avoiding mistakes and misinterpretations. The overarching goal driving this volume is to excite the expert and stimulate the newcomer to the field of Computational Systems Biology.
Cutting-edge and authoritative, Computational Systems Biology in Medicine and Biotechnology: Methods and Protocols is a valuable resource for pre- and post-graduate students in medicine and biotechnology, and in diverse areas ranging from microbiology to cellular and organismal biology, as well as computational and experimental biologists,and researchers interested in utilizing comprehensive systems biology oriented methods.
Editors and Affiliations
Bibliographic Information
Book Title: Computational Systems Biology in Medicine and Biotechnology
Book Subtitle: Methods and Protocols
Editors: Sonia Cortassa, Miguel A. Aon
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-0716-1831-8
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2022
Hardcover ISBN: 978-1-0716-1830-1Published: 24 May 2022
Softcover ISBN: 978-1-0716-1833-2Published: 25 May 2023
eBook ISBN: 978-1-0716-1831-8Published: 23 May 2022
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 493
Number of Illustrations: 21 b/w illustrations, 143 illustrations in colour
Topics: Bioinformatics, Biotechnology