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Meta-Research

Methods and Protocols

  • Book
  • © 2022

Overview

Editors:
  1. Evangelos Evangelou

    1. Department of Hygiene and Epidemiology University of Ioannina Medical School, Department of Epidemiology and Biostatistics Imperial College London London, UK, Ioannina, Greece

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  2. Areti Angeliki Veroniki

    1. Knowledge Translation Program Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Department of Surgery and Cancer Faculty of Medicine Institute of Reproductive and Developmental Biology Imperial College London, UK ISSN, Toronto, Canada

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 2345)

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Table of contents (18 protocols)

  1. Front Matter

    Pages i-xi
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  2. Principles of Systematic Reviews and Meta-analyses

    • Rebecca L. Morgan, Ivan D. Florez
    Pages 1-15

  3. Semi-automated Tools for Systematic Searches

    • Gaelen P. Adam, Byron C. Wallace, Thomas A. Trikalinos
    Pages 17-40

  4. Fixed- and Random-Effects Models

    • Steve Kanters
    Pages 41-65

  5. Assessing Heterogeneity in Random-Effects Meta-analysis

    • Dean Langan
    Pages 67-89

  6. Performing Meta-analyses with Very Few Studies

    • Anke Schulz, Christoph Schürmann, Guido Skipka, Ralf Bender
    Pages 91-102

  7. Systematic Versus Rapid Versus Scoping Reviews

    • Zachary Bouck, Sharon E. Straus, Andrea C. Tricco
    Pages 103-119

  8. Living Systematic Reviews

    • Mark Simmonds, Julian H. Elliott, Anneliese Synnot, Tari Turner
    Pages 121-134

  9. Umbrella Reviews: What They Are and Why We Need Them

    • Stefania I. Papatheodorou, Evangelos Evangelou
    Pages 135-146

  10. Meta-analysis of Pragmatic and Explanatory Trials

    • Lawrence Mbuagbaw, Theresa Aves
    Pages 147-158

  11. Meta-Analysis of Proportions

    • Guido Schwarzer, Gerta Rücker
    Pages 159-172

  12. Meta-Analysis Methods of Diagnostic Test Accuracy Studies

    • Niki Dimou, Pantelis Bagos
    Pages 173-185

  13. Network Meta-Analysis

    • Jennifer Watt, Cinzia Del Giovane
    Pages 187-201

  14. Contrast-Based and Arm-Based Models for Network Meta-Analysis

    • Amalia Karahalios, Joanne E. McKenzie, Ian R. White
    Pages 203-221

  15. Software to Conduct a Meta-Analysis and Network Meta-Analysis

    • Caitlin Daly, Charlene Soobiah
    Pages 223-244

  16. Modeling Multicomponent Interventions in Network Meta-Analysis

    • Areti Angeliki Veroniki, Georgios Seitidis, Stavros Nikolakopoulos, Marta Ballester, Jessica Beltran, Monique Heijmans et al.
    Pages 245-261

  17. Practical Considerations and Challenges When Conducting an Individual Participant Data (IPD) Meta-Analysis

    • Sarah J. Nevitt, Catrin Tudur Smith
    Pages 263-278

  18. Individual Patient Data Meta-Analysis and Network Meta-Analysis

    • Suzanne C. Freeman
    Pages 279-298

  19. Challenges in Comparative Meta-Analysis of the Accuracy of Multiple Diagnostic Tests

    • Areti Angeliki Veroniki, Sofia Tsokani, Gerta Rücker, Dimitris Mavridis, Yemisi Takwoingi
    Pages 299-316

  20. Back Matter

    Pages 317-318
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Keywords

About this book

This volume presents state-of-the art design, analysis and integration approaches for biomedical data including novel statistical models for a comprehensive and powerful synthesis and assessment of scientific evidence. Chapters detail principles of systematic reviews, semi-automated tools for systematic searches, fixed- and random-effects meta-analytical models, living systematic reviews, meta-analysis of genetic studies, meta-analysis of pragmatic and explanatory trials, network meta-analysis, and other modern approaches for data synthesis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials, and tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and cutting-edge, the Meta- Research: Methods and Protocols book, written by global experts, will introduce the reader in a step-by-step process to the methods of the vital and highly promising field of evidence synthesis.

Editors and Affiliations

  • Department of Hygiene and Epidemiology University of Ioannina Medical School, Department of Epidemiology and Biostatistics Imperial College London London, UK, Ioannina, Greece

    Evangelos Evangelou

  • Knowledge Translation Program Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Department of Surgery and Cancer Faculty of Medicine Institute of Reproductive and Developmental Biology Imperial College London, UK ISSN, Toronto, Canada

    Areti Angeliki Veroniki

Bibliographic Information

  • Book Title: Meta-Research

  • Book Subtitle: Methods and Protocols

  • Editors: Evangelos Evangelou, Areti Angeliki Veroniki

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-0716-1566-9

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2022

  • Hardcover ISBN: 978-1-0716-1565-2Published: 23 September 2021

  • Softcover ISBN: 978-1-0716-1568-3Published: 25 September 2021

  • eBook ISBN: 978-1-0716-1566-9Published: 22 September 2021

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XI, 318

  • Number of Illustrations: 21 b/w illustrations, 19 illustrations in colour

  • Topics: Life Sciences, general, Bioinformatics

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