Environmental Toxicology and Toxicogenomics

1. Front Matter

   Pages i-xiii

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2. Animal Toxicity

   1. Front Matter

      Pages 1-1

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   2. Detection of Caenorhabditis elegans Germ Cell Apoptosis Following Exposure to Environmental Contaminant Mixtures: A Crude Oil-Dispersant Mixture Example

      • Joseph Ryan Polli, Mary Farwell, Xiaoping Pan

      Pages 3-18

   3. High-Throughput Measurement for Toxic Effects of Metal Mixtures in Caenorhabditis elegans

      • Kathy S. Xue, Lili Tang

      Pages 19-32

   4. Evaluations of Environmental Pollutant-Induced Mitochondrial Toxicity Using Caenorhabditis elegans as a Model System

      • Fuli Zheng, Michael Aschner, Huangyuan Li

      Pages 33-46

   5. Methods to Assay the Behavior of Drosophila melanogaster for Toxicity Study

      • Guiran Xiao

      Pages 47-54

   6. Investigating the Joint Effects of Pesticides and Ultraviolet B Radiation in Xenopus laevis and Other Amphibians

      • Shuangying Yu, Mike Wages

      Pages 55-66

   7. Identification of Stable Reference Genes for Toxicogenomic and Gene Expression Analysis

      • Xiaoping Pan, Baohong Zhang

      Pages 67-94

   8. Semi-Quantitative RT-PCR: An Effective Method to Explore the Regulation of Gene Transcription Level Affected by Environmental Pollutants

      • Fan Wang

      Pages 95-103

   9. Employing Multiple New Neurobiological Methods to Investigate Environmental Neurotoxicology in Mice

      • Ping Cai, Huangyuan Li

      Pages 105-122

   10. Analyses of Epigenetic Modification in Environmental Pollutants-Induced Neurotoxicity

       • Guangxia Yu, Zhenkun Guo, Huangyuan Li

       Pages 123-141

   11. The Application of Omics Technologies in the Research of Neurotoxicology

       • Wenya Shao, Huangyuan Li

       Pages 143-154

   12. Flow Cytofluorometric Analysis of Molecular Mechanisms of Premature Red Blood Cell Death

       • Mohammad A. Alfhili, Myon Hee Lee

       Pages 155-165

   13. Practical Methods and Technologies in Environmental Epidemiology

       • Chuancheng Wu, Donghong Wei, Huangyuan Li, Siying Wu

       Pages 167-195

   14. In Ovo Early-in-Life Inhalation Exposure to Gas/Aerosol with a Chicken Embryo Model

       • Qixiao Jiang, Xiaohui Xu, Hao Ni, Yajie Guo, Junhua Yuan, Yuxin Zheng

       Pages 197-201

   15. DNA Damage in Liver Cells of the Tilapia Fish Oreochromis mossambicus Larva Induced by the Insecticide Cyantraniliprole at Sublethal Doses During Chronic Exposure

       • Yongmei Fan, Chengbin Xu, Weiguo Miao

       Pages 203-214

3. Plant Toxicity

   1. Front Matter

      Pages 215-215

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   2. Impact of Nanoparticles on Plant Growth, Development, and Biomass

      • Ilya N. Boykov, Baohong Zhang

      Pages 217-224

   3. Biochemical and Physiological Toxicity of Nanoparticles in Plant

      • Zhiyong Zhang, Baohong Zhang

      Pages 225-239

   4. Determination of Oxidative Stress and Antioxidant Enzyme Activity for Physiological Phenotyping During Heavy Metal Exposure

      • Samrana Zahir, Fan Zhang, Jinhong Chen, Shuijin Zhu

      Pages 241-249

This detailed book provides an accessible compendium of up-to-date methods in the fields of environmental toxicology, molecular toxicology, and toxicogenomics. Organized into four major sections, the volume examines methods utilizing model animal species, such as nematode, fruit fly, mice, chicken, and amphibians, methods using plants to study chemical toxicity, applying the Ames assay to chemical mutagenicity study, as well as methods for environmental chemical analysis. Although this book is divided into these parts, the methods can be used across species. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and practical, Environmental Toxicology and Toxicogenomics: Principles, Methods, and Applications serves as a valuable resource for the scientific community, particularly for young scientists and graduate and undergraduate students, inspiring more research in the vitally important field of environmental toxicity, molecular toxicology, and toxicogenomics.

• Environmental pollutants
• Chemical toxicity
• Genotoxicity
• Toxicant exposure
• Environmental chemical analysis
• Molecular toxicology

• Department of Biology, East Carolina University, Greenville, USA

  Xiaoping Pan, Baohong Zhang

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