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Neuromethods

Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy

Editors: Vohora, Divya (Ed.)

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $149.00
price for USA in USD
  • ISBN 978-1-0716-1254-5
  • Digitally watermarked, DRM-free
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  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-1-0716-1253-8
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About this book

This volume discusses the latest experimental and clinical approaches to study seizures and epilepsy. Chapters in this book cover detailed protocols for ex vivo and in vitro experimental models and widely-used in vivo (acute and chronic seizure) models in epilepsy research. Chapters also cover techniques to screen the effective leads for the treatment of refractory seizures of pharmacoresistant epilepsy and invertebrate, non-mammalian models. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. 

Cutting-edge and practical, Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy is a valuable resource for researchers, in both industry and academia, interested in learning about this important and developing field.


Table of contents (13 chapters)

Table of contents (13 chapters)
  • Models of Seizures and Epilepsy: Important Tools in the Discovery and Evaluation of Novel Epilepsy Therapies

    Pages 3-7

    Löscher, Wolfgang

  • Protocol for Rodent Organotypic Hippocampal Slice Culture Model for Ex Vivo Monitoring of Epileptogenesis

    Pages 11-28

    Ghiasvand, Shabnam (et al.)

  • Methods for the Screening of New Chemical Entities for Deciphering Neuroinflammatory and Associated Pathways in Seizures: An In Vitro Perspective

    Pages 29-53

    Vyas, Preeti (et al.)

  • Cellular Electrophysiological Methods to Decipher the Altered Synaptic Transmission Associated with Drug-Resistant Epilepsy

    Pages 55-76

    Dey, Soumil (et al.)

  • Acute Seizure Tests Used in Epilepsy Research: Step-by-Step Protocol of the Maximal Electroshock Seizure (MES) Test, the Maximal Electroshock Seizure Threshold (MEST) Test, and the Pentylenetetrazole (PTZ)-Induced Seizure Test in Rodents

    Pages 79-102

    Socała, Katarzyna (et al.)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-1-0716-1254-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-1-0716-1253-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy
Editors
  • Divya Vohora
Series Title
Neuromethods
Series Volume
167
Copyright
2021
Publisher
Springer US
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-0716-1254-5
DOI
10.1007/978-1-0716-1254-5
Hardcover ISBN
978-1-0716-1253-8
Series ISSN
0893-2336
Edition Number
1
Number of Pages
XIV, 250
Number of Illustrations
13 b/w illustrations, 24 illustrations in colour
Topics