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  • © 2021

Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy

Editors:

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 167)

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Table of contents (13 protocols)

  1. Front Matter

    Pages i-xiv
  2. Models for Seizures and Epilepsy: An Overview

    1. Front Matter

      Pages 1-1
  3. Ex Vivo and In Vitro Models

    1. Front Matter

      Pages 9-9
    2. Protocol for Rodent Organotypic Hippocampal Slice Culture Model for Ex Vivo Monitoring of Epileptogenesis

      • Shabnam Ghiasvand, Jing Liu, Md. Joynal Abedin, Yevgeny Berdichevsky
      Pages 11-28
    3. Cellular Electrophysiological Methods to Decipher the Altered Synaptic Transmission Associated with Drug-Resistant Epilepsy

      • Soumil Dey, Aparna Banerjee Dixit, Manjari Tripathi, P. Sarat Chandra, Jyotirmoy Banerjee
      Pages 55-76
  4. Models for Refractory Seizures

    1. Front Matter

      Pages 165-165
  5. Invertebrate/Non-Mammalian Models

    1. Front Matter

      Pages 219-219
    2. Methods to Investigate Seizures and Associated Cognitive Decline Using Zebrafish Model

      • Brandon Kar Meng Choo, Mohd. Farooq Shaikh
      Pages 221-232
    3. C. elegans as a Potential Model for Acute Seizure-Like Activity

      • Alistair Jones, Anthony G. Marson, Vincent T. Cunliffe, Graeme J. Sills, Alan Morgan
      Pages 233-248
  6. Back Matter

    Pages 249-250

About this book

This volume discusses the latest experimental and clinical approaches to study seizures and epilepsy. Chapters in this book cover detailed protocols for ex vivo and in vitro experimental models and widely-used in vivo (acute and chronic seizure) models in epilepsy research. Chapters also cover techniques to screen the effective leads for the treatment of refractory seizures of pharmacoresistant epilepsy and invertebrate, non-mammalian models. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. 

Cutting-edge and practical, Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy is a valuable resource for researchers, in both industry and academia, interested in learning about this important and developing field.



Editors and Affiliations

  • Neurobehavioral Pharmacology Laboratory, Department of Pharmacology, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi, India

    Divya Vohora

Bibliographic Information

  • Book Title: Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy

  • Editors: Divya Vohora

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-0716-1254-5

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2021

  • Hardcover ISBN: 978-1-0716-1253-8Published: 08 June 2021

  • Softcover ISBN: 978-1-0716-1256-9Published: 08 June 2021

  • eBook ISBN: 978-1-0716-1254-5Published: 07 June 2021

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XIV, 250

  • Number of Illustrations: 13 b/w illustrations, 24 illustrations in colour

  • Topics: Neurosciences

Buy it now

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access