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Methods in Molecular Biology

Toxicity Assessment

Methods and Protocols

Editors: Palmeira, Carlos Manuel M., de Oliveira, Danielle Palma, Dorta, Daniel Junqueira (Eds.)

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  • Includes cutting-edge techniques
  • Provides step-by-step detail reproducible for reproducible results
  • Contains key implementation advice from the experts
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eBook $149.00
price for USA in USD
  • ISBN 978-1-0716-1091-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
About this book

This book collects protocols from different areas of knowledge to assist in the identification of toxic effects exerted by different xenobiotics. At the same time as classical techniques are presented, modern techniques with alternative models to the use of animals are also presented. Given the ever-increasing exposure to different compounds and their effects on population health, the assessment of multiple endpoints is of utmost importance for better risk assessment, and this collection addresses that need. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and practical, Toxicity Assessment: Methods and Protocols aims to serve researchers in this vast field of science as they seek to better understand the mechanisms of action of different xenobiotics.

Table of contents (17 chapters)

Table of contents (17 chapters)
  • The Single-Cell Gel Electrophoresis Genotoxin Sensitivity Assay

    Pages 1-12

    Ferk, Franziska (et al.)

  • Skin Sensitization Tests: The LLNA and the RhE IL-18 Potency Assay

    Pages 13-29

    Corsini, Emanuela (et al.)

  • Skin Equivalent Models: Protocols for In Vitro Reconstruction for Dermal Toxicity Evaluation

    Pages 31-41

    Nascimento Pedrosa, Tatiana (et al.)

  • Intravital Microscopy: A Tool to Investigate the Toxicity in the Immune System, Vessel Rheology, and Xenobiotic Distribution

    Pages 43-55

    Hebeda, Cristina Bichels (et al.)

  • Cell-Based Biosensor to Visualize Nitric Oxide Release from Living Cells for Toxicity Assessment

    Pages 57-64

    Sato, Moritoshi (et al.)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-1-0716-1091-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Toxicity Assessment
Book Subtitle
Methods and Protocols
Editors
  • Carlos Manuel M. Palmeira
  • Danielle Palma de Oliveira
  • Daniel Junqueira Dorta
Series Title
Methods in Molecular Biology
Series Volume
2240
Copyright
2021
Publisher
Springer US
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-0716-1091-6
DOI
10.1007/978-1-0716-1091-6
Hardcover ISBN
978-1-0716-1090-9
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XII, 266
Number of Illustrations
10 b/w illustrations, 68 illustrations in colour
Topics