Methods in Molecular Biology

Mouse Genetics

Methods and Protocols

Editors: Singh, Shree Ram, Hoffman, Robert M., Fernandez-funez, Pedro (Eds.)

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  • Includes cutting-edge techniques
  • Provides step-by-step detail essential for reproducible results
  • Contains key implementation advice from the experts
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eBook $149.00
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  • ISBN 978-1-0716-1008-4
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Hardcover $199.99
price for USA in USD
  • ISBN 978-1-0716-1007-7
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About this book

This fully updated edition provides selected mouse genetic techniques and their application in modeling varieties of human diseases. The chapters are mainly focused on the generation of different transgenic mice to accomplish the manipulation of genes of interest, tracing cell lineages, and modeling human diseases. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and up-to-date, Mouse Genetics: Methods and Protocols, Second Edition delivers fundamental techniques and protocols to geneticists, molecular biologists, cell and developmental biologists, students, and postdoctoral fellows working in the various disciplines of genetics, developmental biology, mouse genetics, and modeling human diseases.

Table of contents (15 chapters)

Table of contents (15 chapters)
  • Generation of Mouse Model (KI and CKO) via Easi-CRISPR

    Pages 1-27

    Shola, Dorjee T. N. (et al.)

  • Analysis of Gene Expression Using lacZ Reporter Mouse Lines

    Pages 29-45

    Krämer, Michael Simon (et al.)

  • Linear Density Sucrose Gradients to Study Mitoribosomal Biogenesis in Tissue-Specific Knockout Mice

    Pages 47-60

    Ruzzenente, Benedetta (et al.)

  • Mouse Models for Studying Hippocampal Adult Neural Stem Cell Biology

    Pages 61-74

    Semerci, Fatih (et al.)

  • Retina as a Model to Study In Vivo Transmission of α-Synuclein in the A53T Mouse Model of Parkinson’s Disease

    Pages 75-85

    Mammadova, Najiba (et al.)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-1-0716-1008-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-1-0716-1007-7
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Mouse Genetics
Book Subtitle
Methods and Protocols
Editors
  • Shree Ram Singh
  • Robert M. Hoffman
  • Pedro Fernandez-funez
Series Title
Methods in Molecular Biology
Series Volume
2224
Copyright
2021
Publisher
Springer US
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-0716-1008-4
DOI
10.1007/978-1-0716-1008-4
Hardcover ISBN
978-1-0716-1007-7
Series ISSN
1064-3745
Edition Number
2
Number of Pages
XI, 217
Number of Illustrations
6 b/w illustrations, 41 illustrations in colour
Topics