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  • © 2021

Clinical Trials In Parkinson's Disease

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 160)

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Table of contents (15 protocols)

  1. Front Matter

    Pages i-xv
  2. Preclinical Models of Parkinson’s Disease

    1. Front Matter

      Pages 1-1
    2. Toxin-Based Rodent Models of Parkinson’s Disease

      • M. Angela Cenci, VĂ©ronique Sgambato
      Pages 3-19
    3. Assessment of Nonmotor Symptoms in Rodent Models of Parkinson’s Disease

      • Francesca Rossi, Manolo Carta, Elisabetta Tronci
      Pages 21-36
    4. Genetic Models of Parkinson’s Disease

      • Philippe Kachidian, Paolo Gubellini
      Pages 37-84
  3. Clinical Trials for Motor Symptoms in Parkinson’s Disease

    1. Front Matter

      Pages 85-85
    2. Clinical Trials for Motor Complications in Parkinson’s Disease

      • Tiago A. Mestre, Joaquim J. Ferreira, Olivier Rascol
      Pages 109-135
    3. Clinical Trials for Gait Disorders in Parkinson’s Disease

      • Zuzana Kosutzka, Urban M. Fietzek, Peter Valkovic
      Pages 137-159
    4. Value and Methods of Pharmacovigilance in the Monitoring of Drug Safety in Parkinson’s Disease

      • Santiago Perez-Lloret, James A. G. Crispo, Maria Veronica Rey, Donald Mattison, Daniel Krewski
      Pages 177-190
  4. Clinical Trials for Nonmotor Symptoms in Parkinson’s Disease

    1. Front Matter

      Pages 191-191
    2. Clinical Trials on Management of Pain in Parkinson’s Disease

      • Azman Aris, Katarina Rukavina, Raquel Taddei, Alexandra Rizos, Anna Sauerbier, K. Ray Chaudhuri
      Pages 293-321
    3. Clinical Trials for Erectile Dysfunction in Parkinson’s Disease

      • Shen-Yang Lim, Ai Huey Tan, Mathis Grossmann
      Pages 367-377
  5. Back Matter

    Pages 395-396

About this book

This volume looks at major clinical trials for motor and non-motor symptoms in Parkinson’s Disease (PD) and covers important aspects, including trial design, sample selection, and outcome selection. Chapters in this book discuss topics such as toxin-based rodent or genetic models of PD; clinical trials for motor symptoms, L-DOPA related motor complications, and gait disorders; clinical trials for mood disorders, troubled sleep, autonomic dysfunction; and clinical trials for disease modifying therapies. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory or research center.


Cutting-edge and authoritative, Clinical Trials in Parkinson’s Disease is a valuable resource for clinicians and researchers who want to enhance their interpretation of results from clinical trials and to design their own high-quality trials.   


Editors and Affiliations

  • National Research Council (CAECHIS-UAI), Buenos Aires, Argentina

    Santiago Perez-Lloret

Bibliographic Information

  • Book Title: Clinical Trials In Parkinson's Disease

  • Editors: Santiago Perez-Lloret

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-0716-0912-5

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2021

  • Hardcover ISBN: 978-1-0716-0911-8Published: 19 August 2020

  • Softcover ISBN: 978-1-0716-0914-9Published: 19 August 2021

  • eBook ISBN: 978-1-0716-0912-5Published: 17 August 2020

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XV, 396

  • Number of Illustrations: 5 b/w illustrations, 5 illustrations in colour

  • Topics: Neurosciences

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access