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Methods in Molecular Biology
cover

Animal Models of Diabetes

Methods and Protocols

Editors: King, Aileen (Ed.)

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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  • ISBN 978-1-07-160385-7
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  • ISBN 978-1-07-160384-0
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About this book

This volume discusses a variety of animal models of diabetes, as well as describes techniques used to study end-points when using these models. The chapters in this book cover topics such as important considerations when working with mouse models of diabetes, highlighting factors that new investigators may not be aware of and some potential pitfalls in experimental outcomes; main characteristics of some commonly used animal models of diabetes research, ranging from mice to primates; animal models used to study specific aspects of beta-cell biology; and a focus on techniques used to assess blood glucose homeostasis, insulin action, and islet function in vivo and ex vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and comprehensive, Animal Models of Diabetes: Methods and Protocols is a valuable resource that will help diabetes researchers design and carry out in vivo studies that will best suit their experimental questions and needs.  

Table of contents (21 chapters)

Table of contents (21 chapters)
  • Practical Considerations when Using Mouse Models of Diabetes

    Pages 1-10

    King, Aileen J. F. (et al.)

  • An Overview of Rodent Models of Obesity and Type 2 Diabetes

    Pages 11-24

    Lutz, Thomas A.

  • Selectively Bred Diabetes Models: GK Rats, NSY Mice, and ON Mice

    Pages 25-54

    Nagao, Mototsugu (et al.)

  • A Review of Mouse Models of Monogenic Diabetes and ER Stress Signaling

    Pages 55-67

    Salpea, Paraskevi (et al.)

  • Rat Models of Human Type 1 Diabetes

    Pages 69-85

    Lenzen, Sigurd (et al.)

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-07-160385-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-07-160384-0
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Animal Models of Diabetes
Book Subtitle
Methods and Protocols
Editors
  • Aileen King
Series Title
Methods in Molecular Biology
Series Volume
2128
Copyright
2020
Publisher
Springer US
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-07-160385-7
DOI
10.1007/978-1-0716-0385-7
Hardcover ISBN
978-1-07-160384-0
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 342
Number of Illustrations
10 b/w illustrations, 39 illustrations in colour
Topics

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